Methodological issues and inconsistencies in the field of omega-3 fatty acids research

This source preferred by Simon Dyall

Authors: Dyall, S.

Journal: Prostaglandins, Leukotrienes and Essential Fatty Acids

Volume: 85

Issue: 5

Pages: 281-285

This data was imported from PubMed:

Authors: Dyall, S.C.

Journal: Prostaglandins Leukot Essent Fatty Acids

Volume: 85

Issue: 5

Pages: 281-285

eISSN: 1532-2823

DOI: 10.1016/j.plefa.2011.04.009

There is growing interest into researching omega-3 fatty acids; however, there are considerable variations in the methodologies employed. Many studies add oils to animal feed and under ambient conditions omega-3 fatty acids are particularly unstable and prone to autoxidation and peroxidative damage. It is therefore important to take specific precautions with the stock preparations and when preparing the experimental diets. There is a need for clarity in the reporting of methodologies employed, such as how oil preparations are stored and handled, how experimental diets are prepared, the potential effects of adding additional antioxidants, whether there is a clear rationale for the selection of control/placebo diets, which may be situation dependent, and consistency in expressing the experimental doses. The purpose of this article is to highlight some of these issues in the hope of promoting discussion, and potentially developing guidelines as to what represents best practice.

This data was imported from Scopus:

Authors: Dyall, S.C.

Journal: Prostaglandins Leukotrienes and Essential Fatty Acids

Volume: 85

Issue: 5

Pages: 281-285

eISSN: 1532-2823

ISSN: 0952-3278

DOI: 10.1016/j.plefa.2011.04.009

There is growing interest into researching omega-3 fatty acids; however, there are considerable variations in the methodologies employed. Many studies add oils to animal feed and under ambient conditions omega-3 fatty acids are particularly unstable and prone to autoxidation and peroxidative damage. It is therefore important to take specific precautions with the stock preparations and when preparing the experimental diets. There is a need for clarity in the reporting of methodologies employed, such as how oil preparations are stored and handled, how experimental diets are prepared, the potential effects of adding additional antioxidants, whether there is a clear rationale for the selection of control/placebo diets, which may be situation dependent, and consistency in expressing the experimental doses. The purpose of this article is to highlight some of these issues in the hope of promoting discussion, and potentially developing guidelines as to what represents best practice. © 2011 Elsevier Ltd.

This data was imported from Web of Science (Lite):

Authors: Dyall, S.C.

Journal: PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS

Volume: 85

Issue: 5

Pages: 281-285

ISSN: 0952-3278

DOI: 10.1016/j.plefa.2011.04.009

This data was imported from Europe PubMed Central:

Authors: Dyall, S.C.

Journal: Prostaglandins, leukotrienes, and essential fatty acids

Volume: 85

Issue: 5

Pages: 281-285

eISSN: 1532-2823

ISSN: 0952-3278

There is growing interest into researching omega-3 fatty acids; however, there are considerable variations in the methodologies employed. Many studies add oils to animal feed and under ambient conditions omega-3 fatty acids are particularly unstable and prone to autoxidation and peroxidative damage. It is therefore important to take specific precautions with the stock preparations and when preparing the experimental diets. There is a need for clarity in the reporting of methodologies employed, such as how oil preparations are stored and handled, how experimental diets are prepared, the potential effects of adding additional antioxidants, whether there is a clear rationale for the selection of control/placebo diets, which may be situation dependent, and consistency in expressing the experimental doses. The purpose of this article is to highlight some of these issues in the hope of promoting discussion, and potentially developing guidelines as to what represents best practice.

The data on this page was last updated at 04:40 on November 22, 2017.