A meta-analysis of prevalence rates and moderating factors for cancer-related post-traumatic stress disorder

This source preferred by Tamas Hickish and Gareth Abbey

Authors: Abbey, G., Thompson, S.B.N. and Hickish, T.

http://eprints.bournemouth.ac.uk/24879/

Journal: Psycho-Oncology

Volume: 24

Issue: 4

Pages: 371-381

DOI: 10.1002/pon.3654

This source preferred by Tamas Hickish and Gareth Abbey

Authors: Abbey, G., Thompson, S.B.N., Heathcote, D. and Hickish, T.

http://eprints.bournemouth.ac.uk/24879/

Journal: Psych-Oncology

Volume: Volume 24, Issue 4 April 2015 Pages 371–381

Issue: 4

Pages: 7-7

This source preferred by Tamas Hickish and Gareth Abbey

Authors: Abbey, G., Thompson, S., Hickish, T. and Heathcote, D.

http://eprints.bournemouth.ac.uk/24879/

Journal: Psycho-Oncology

Volume: 24

Issue: 4

Pages: 371-381

ISSN: 1057-9249

DOI: 10.1002/pon.3654

Objective

Systematic reviews highlight a broad range of cancer-related post-traumatic stress disorder (CR-PTSD) prevalence estimates in cancer survivors. This meta-analysis was conducted to provide a prevalence estimate of significant CR-PTSD symptoms and full diagnoses to facilitate the psychological aftercare of cancer survivors.

Methods

A systematic literature search was conducted for studies using samples of cancer survivors by using validated clinical interviews and questionnaires to assess the prevalence of CR-PTSD (k = 25, n = 4189). Prevalence estimates were calculated for each assessment method using random-effects meta-analysis. Mixed-effects meta-regression and categorical analyses were used to investigate study-level moderator effects.

Results

Studies using the PTSD Checklist—Civilian Version yielded lower event rates using cut-off [7.3%, 95% confidence intervals (CI) = 4.5–11.7, k = 10] than symptom cluster (11.2%, 95% CI = 8.7–14.4, k = 9). Studies using the Structured Clinical Interview for Diagnostic and Statistical Manual, Fourth Edition (SCID), yielded low rates for lifetime (15.3%, 95% CI = 9.1–25, k = 5) and current CR-PTSD (5.1%, 95% CI = 2.8–8.9, k = 9). Between-study heterogeneity was substantial (I2 = 54–87%). Studies with advanced-stage samples yielded significantly higher rates with PTSD Checklist—Civilian Version cluster scoring (p = 0.05), and when assessing current CR-PTSD on the SCID (p = 0.05). The effect of mean age on current PTSD prevalence met significance on the SCID (p = 0.05). SCID lifetime prevalence rates decreased with time post-treatment (R2 = 0.56, p < 0.05).

Discussion

The cancer experience is sufficiently traumatic to induce PTSD in a minority of cancer survivors. Post-hoc analyses suggest that those who are younger, are diagnosed with more advanced disease and recently completed treatment may be at greater risk of PTSD. More research is needed to investigate vulnerability factors for PTSD in cancer survivors.

This data was imported from PubMed:

Authors: Abbey, G., Thompson, S.B.N., Hickish, T. and Heathcote, D.

http://eprints.bournemouth.ac.uk/24879/

Journal: Psychooncology

Volume: 24

Issue: 4

Pages: 371-381

eISSN: 1099-1611

DOI: 10.1002/pon.3654

OBJECTIVE: Systematic reviews highlight a broad range of cancer-related post-traumatic stress disorder (CR-PTSD) prevalence estimates in cancer survivors. This meta-analysis was conducted to provide a prevalence estimate of significant CR-PTSD symptoms and full diagnoses to facilitate the psychological aftercare of cancer survivors. METHODS: A systematic literature search was conducted for studies using samples of cancer survivors by using validated clinical interviews and questionnaires to assess the prevalence of CR-PTSD (k = 25, n = 4189). Prevalence estimates were calculated for each assessment method using random-effects meta-analysis. Mixed-effects meta-regression and categorical analyses were used to investigate study-level moderator effects. RESULTS: Studies using the PTSD Checklist-Civilian Version yielded lower event rates using cut-off [7.3%, 95% confidence intervals (CI) = 4.5-11.7, k = 10] than symptom cluster (11.2%, 95% CI = 8.7-14.4, k = 9). Studies using the Structured Clinical Interview for Diagnostic and Statistical Manual, Fourth Edition (SCID), yielded low rates for lifetime (15.3%, 95% CI = 9.1-25, k = 5) and current CR-PTSD (5.1%, 95% CI = 2.8-8.9, k = 9). Between-study heterogeneity was substantial (I(2)  = 54-87%). Studies with advanced-stage samples yielded significantly higher rates with PTSD Checklist-Civilian Version cluster scoring (p = 0.05), and when assessing current CR-PTSD on the SCID (p = 0.05). The effect of mean age on current PTSD prevalence met significance on the SCID (p = 0.05). SCID lifetime prevalence rates decreased with time post-treatment (R(2)  = 0.56, p < 0.05). DISCUSSION: The cancer experience is sufficiently traumatic to induce PTSD in a minority of cancer survivors. Post-hoc analyses suggest that those who are younger, are diagnosed with more advanced disease and recently completed treatment may be at greater risk of PTSD. More research is needed to investigate vulnerability factors for PTSD in cancer survivors. © 2014 The Authors. Psycho-Oncology published by John Wiley & Sons Ltd.

This source preferred by Simon Thompson

This data was imported from Scopus:

Authors: Abbey, G., Thompson, S.B.N., Hickish, T. and Heathcote, D.

http://eprints.bournemouth.ac.uk/24879/

Journal: Psycho-Oncology

eISSN: 1099-1611

ISSN: 1057-9249

DOI: 10.1002/pon.3654

Objective: Systematic reviews highlight a broad range of cancer-related post-traumatic stress disorder (CR-PTSD) prevalence estimates in cancer survivors. This meta-analysis was conducted to provide a prevalence estimate of significant CR-PTSD symptoms and full diagnoses to facilitate the psychological aftercare of cancer survivors. Methods: A systematic literature search was conducted for studies using samples of cancer survivors by using validated clinical interviews and questionnaires to assess the prevalence of CR-PTSD (k=25, n=4189). Prevalence estimates were calculated for each assessment method using random-effects meta-analysis. Mixed-effects meta-regression and categorical analyses were used to investigate study-level moderator effects. Results: Studies using the PTSD Checklist-Civilian Version yielded lower event rates using cut-off [7.3%, 95% confidence intervals (CI)=4.5-11.7, k=10] than symptom cluster (11.2%, 95% CI=8.7-14.4, k=9). Studies using the Structured Clinical Interview for Diagnostic and Statistical Manual, Fourth Edition (SCID), yielded low rates for lifetime (15.3%, 95% CI=9.1-25, k=5) and current CR-PTSD (5.1%, 95% CI=2.8-8.9, k=9). Between-study heterogeneity was substantial (I 2 =54-87%). Studies with advanced-stage samples yielded significantly higher rates with PTSD Checklist-Civilian Version cluster scoring (p=0.05), and when assessing current CR-PTSD on the SCID (p=0.05). The effect of mean age on current PTSD prevalence met significance on the SCID (p=0.05). SCID lifetime prevalence rates decreased with time post-treatment (R 2 =0.56, p < 0.05). Discussion: The cancer experience is sufficiently traumatic to induce PTSD in a minority of cancer survivors. Post-hoc analyses suggest that those who are younger, are diagnosed with more advanced disease and recently completed treatment may be at greater risk of PTSD. More research is needed to investigate vulnerability factors for PTSD in cancer survivors. © 2014 The Authors.

This data was imported from Web of Science (Lite):

Authors: Abbey, G., Thompson, S., Heathcote, D. and Hickish, T.

http://eprints.bournemouth.ac.uk/24879/

Journal: PSYCHO-ONCOLOGY

Volume: 23

Pages: 7

eISSN: 1099-1611

ISSN: 1057-9249

This data was imported from Europe PubMed Central:

Authors: Abbey, G., Thompson, S.B., Hickish, T. and Heathcote, D.

http://eprints.bournemouth.ac.uk/24879/

Journal: Psycho-oncology

Volume: 24

Issue: 4

Pages: 371-381

eISSN: 1099-1611

ISSN: 1057-9249

Systematic reviews highlight a broad range of cancer-related post-traumatic stress disorder (CR-PTSD) prevalence estimates in cancer survivors. This meta-analysis was conducted to provide a prevalence estimate of significant CR-PTSD symptoms and full diagnoses to facilitate the psychological aftercare of cancer survivors.A systematic literature search was conducted for studies using samples of cancer survivors by using validated clinical interviews and questionnaires to assess the prevalence of CR-PTSD (k = 25, n = 4189). Prevalence estimates were calculated for each assessment method using random-effects meta-analysis. Mixed-effects meta-regression and categorical analyses were used to investigate study-level moderator effects.Studies using the PTSD Checklist-Civilian Version yielded lower event rates using cut-off [7.3%, 95% confidence intervals (CI) = 4.5-11.7, k = 10] than symptom cluster (11.2%, 95% CI = 8.7-14.4, k = 9). Studies using the Structured Clinical Interview for Diagnostic and Statistical Manual, Fourth Edition (SCID), yielded low rates for lifetime (15.3%, 95% CI = 9.1-25, k = 5) and current CR-PTSD (5.1%, 95% CI = 2.8-8.9, k = 9). Between-study heterogeneity was substantial (I(2)  = 54-87%). Studies with advanced-stage samples yielded significantly higher rates with PTSD Checklist-Civilian Version cluster scoring (p = 0.05), and when assessing current CR-PTSD on the SCID (p = 0.05). The effect of mean age on current PTSD prevalence met significance on the SCID (p = 0.05). SCID lifetime prevalence rates decreased with time post-treatment (R(2)  = 0.56, p < 0.05).The cancer experience is sufficiently traumatic to induce PTSD in a minority of cancer survivors. Post-hoc analyses suggest that those who are younger, are diagnosed with more advanced disease and recently completed treatment may be at greater risk of PTSD. More research is needed to investigate vulnerability factors for PTSD in cancer survivors. © 2014 The Authors. Psycho-Oncology published by John Wiley & Sons Ltd.

The data on this page was last updated at 04:45 on January 22, 2018.