Perforated duodenal ulcer and cigarette smoking

Authors: Smedley, F., Hickish, T., Taube, M., Yale, C., Leach, R. and Wastell, C.

Journal: Journal of the Royal Society of Medicine

Volume: 81

Issue: 2

Pages: 92-94

ISSN: 0141-0768

DOI: 10.1177/014107688808100214

Abstract:

Whilst the association between smoking and peptic ulceration has been reported previously, the relationship between smoking and the complications of ulcers, such as perforation, bleeding or acute painful exacerbation, has not been examined. In a retrospective study comparing 275 emergency admissions for peptic ulcer with 275 controls, cigarette smoking was significantly more common only in those with a perforated duodenal ulcer. Of 128 patients with perforated duodenal ulcers, 110 (86%) were cigarette smokers compared with 65 (51%) of the 128 matched controls (χ2, P < 0.01). Cigarette smoking in patients with bleeding or acutely exacerbated ulcers was not significantly more common than in controls. These findings strongly suggest a particular association between smoking and perforated duodenal ulcer.

Source: Scopus

Perforated duodenal ulcer and cigarette smoking.

Authors: Smedley, F., Hickish, T., Taube, M., Yale, C., Leach, R. and Wastell, C.

Journal: J R Soc Med

Volume: 81

Issue: 2

Pages: 92-94

ISSN: 0141-0768

DOI: 10.1177/014107688808100214

Abstract:

Whilst the association between smoking and peptic ulceration has been reported previously, the relationship between smoking and the complications of ulcers, such as perforation, bleeding or acute painful exacerbation, has not been examined. In a retrospective study comparing 275 emergency admissions for peptic ulcer with 275 controls, cigarette smoking was significantly more common only in those with a perforated duodenal ulcer. Of 128 patients with perforated duodenal ulcers, 110 (86%) were cigarette smokers compared with 65 (51%) of the 128 matched controls (X2, P less than 0.01). Cigarette smoking in patients with bleeding or acutely exacerbated ulcers was not significantly more common than in controls. These findings strongly suggest a particular association between smoking and perforated duodenal ulcer.

Source: PubMed

Preferred by: Tamas Hickish

PERFORATED DUODENAL-ULCER AND CIGARETTE-SMOKING

Authors: SMEDLEY, F., HICKISH, T., TAUBE, M., YALE, C., LEACH, R. and WASTELL, C.

Journal: JOURNAL OF THE ROYAL SOCIETY OF MEDICINE

Volume: 81

Issue: 2

Pages: 92-94

eISSN: 1758-1095

ISSN: 0141-0768

DOI: 10.1177/014107688808100214

Source: Web of Science (Lite)

Perforated duodenal ulcer and cigarette smoking.

Authors: Smedley, F., Hickish, T., Taube, M., Yale, C., Leach, R. and Wastell, C.

Journal: Journal of the Royal Society of Medicine

Volume: 81

Issue: 2

Pages: 92-94

eISSN: 1758-1095

ISSN: 0141-0768

DOI: 10.1177/014107688808100214

Abstract:

Whilst the association between smoking and peptic ulceration has been reported previously, the relationship between smoking and the complications of ulcers, such as perforation, bleeding or acute painful exacerbation, has not been examined. In a retrospective study comparing 275 emergency admissions for peptic ulcer with 275 controls, cigarette smoking was significantly more common only in those with a perforated duodenal ulcer. Of 128 patients with perforated duodenal ulcers, 110 (86%) were cigarette smokers compared with 65 (51%) of the 128 matched controls (X2, P less than 0.01). Cigarette smoking in patients with bleeding or acutely exacerbated ulcers was not significantly more common than in controls. These findings strongly suggest a particular association between smoking and perforated duodenal ulcer.

Source: Europe PubMed Central