Optimizing bicoid signal extraction

Authors: Hassani, H., Silva, E.S. and Ghodsi, Z.

Journal: Mathematical Biosciences

Volume: 294

Pages: 46-56

eISSN: 1879-3134

ISSN: 0025-5564

DOI: 10.1016/j.mbs.2017.09.008

Abstract:

Signal extraction and analysis is of great importance, not only in fields such as economics and meteorology, but also in genetics and even biomedicine. There exists a range of parametric and nonparametric techniques which can perform signal extractions. However, the aim of this paper is to define a new approach for optimising signal extraction from bicoid gene expression profile. Having studied both parametric and nonparametric signal extraction techniques, we identified the lack of specific criteria enabling users to select the optimal signal extraction parameters. Exploiting the expression profile of bicoid gene, which is a maternal segmentation coordinate gene found in Drosophila melanogaster, we introduce a new approach for optimising the signal extraction using a nonparametric technique. The underlying criteria are based on the distribution of the residual, more specifically its skewness.

https://eprints.bournemouth.ac.uk/30069/

Source: Scopus

Optimizing bicoid signal extraction.

Authors: Hassani, H., Silva, E.S. and Ghodsi, Z.

Journal: Math Biosci

Volume: 294

Pages: 46-56

eISSN: 1879-3134

DOI: 10.1016/j.mbs.2017.09.008

Abstract:

Signal extraction and analysis is of great importance, not only in fields such as economics and meteorology, but also in genetics and even biomedicine. There exists a range of parametric and nonparametric techniques which can perform signal extractions. However, the aim of this paper is to define a new approach for optimising signal extraction from bicoid gene expression profile. Having studied both parametric and nonparametric signal extraction techniques, we identified the lack of specific criteria enabling users to select the optimal signal extraction parameters. Exploiting the expression profile of bicoid gene, which is a maternal segmentation coordinate gene found in Drosophila melanogaster, we introduce a new approach for optimising the signal extraction using a nonparametric technique. The underlying criteria are based on the distribution of the residual, more specifically its skewness.

https://eprints.bournemouth.ac.uk/30069/

Source: PubMed

Optimizing bicoid signal extraction

Authors: Hassani, H., Silva, E.S. and Ghodsi, Z.

Journal: MATHEMATICAL BIOSCIENCES

Volume: 294

Pages: 46-56

eISSN: 1879-3134

ISSN: 0025-5564

DOI: 10.1016/j.mbs.2017.09.008

https://eprints.bournemouth.ac.uk/30069/

Source: Web of Science (Lite)

Optimizing bicoid signal extraction.

Authors: Hassani, H., Silva, E.S. and Ghodsi, Z.

Journal: Mathematical biosciences

Volume: 294

Pages: 46-56

eISSN: 1879-3134

ISSN: 0025-5564

DOI: 10.1016/j.mbs.2017.09.008

Abstract:

Signal extraction and analysis is of great importance, not only in fields such as economics and meteorology, but also in genetics and even biomedicine. There exists a range of parametric and nonparametric techniques which can perform signal extractions. However, the aim of this paper is to define a new approach for optimising signal extraction from bicoid gene expression profile. Having studied both parametric and nonparametric signal extraction techniques, we identified the lack of specific criteria enabling users to select the optimal signal extraction parameters. Exploiting the expression profile of bicoid gene, which is a maternal segmentation coordinate gene found in Drosophila melanogaster, we introduce a new approach for optimising the signal extraction using a nonparametric technique. The underlying criteria are based on the distribution of the residual, more specifically its skewness.

https://eprints.bournemouth.ac.uk/30069/

Source: Europe PubMed Central

Optimizing bicoid signal extraction.

Authors: Hassani, H., Silva, E.S. and Ghodsi, Z.

Journal: Mathematical Biosciences

Volume: 294

Issue: December

Pages: 46-56

ISSN: 0025-5564

Abstract:

Signal extraction and analysis is of great importance, not only in fields such as economics and meteorology, but also in genetics and even biomedicine. There exists a range of parametric and nonparametric techniques which can perform signal extractions. However, the aim of this paper is to define a new approach for optimising signal extraction from bicoid gene expression profile. Having studied both parametric and nonparametric signal extraction techniques, we identified the lack of specific criteria enabling users to select the optimal signal extraction parameters. Exploiting the expression profile of bicoid gene, which is a maternal segmentation coordinate gene found in Drosophila melanogaster, we introduce a new approach for optimising the signal extraction using a nonparametric technique. The underlying criteria are based on the distribution of the residual, more specifically its skewness.

https://eprints.bournemouth.ac.uk/30069/

Source: BURO EPrints