Collection of analytical data for benzodiazepines and benzophenones

Authors: Japp, M., Garthwaite, K., Geeson, A.V. and Osselton, M.D.

Journal: Journal of Chromatography A

Volume: 439

Issue: 2

Pages: 317-339

ISSN: 0021-9673

DOI: 10.1016/S0021-9673(01)83844-9

Abstract:

On April 1st, 1986, amendments were made to Schedule 2 to the Misuse of Drugs Act 1971 such that 33 benzodiazepines became controlled as Class C drugs in the U.K. An analytical database has been prepared to aid the detection and identification of controlled benzodiazepines. Chromatographic properties have been measured including gas chromatography (GC) retention index values, high-performance liquid chromatography (HPLC) capacity factors and thin-layer chromatography (TLC) RF × 100 values. UV spectroscopic and mass spectrometric (MS) data have also been recorded. Analytical data (GC, TLC and MS) are also presented for benzophenones which were produced by acid hydrolysis of the parent benzodiazepines. © 1988.

Source: Scopus

Collection of analytical data for benzodiazepines and benzophenones.

Authors: Japp, M., Garthwaite, K., Geeson, A.V. and Osselton, M.D.

Journal: J Chromatogr

Volume: 439

Issue: 2

Pages: 317-339

DOI: 10.1016/s0021-9673(01)83844-9

Abstract:

On April 1st, 1986, amendments were made to Schedule 2 to the Misuse of Drugs Act 1971 such that 33 benzodiazepines became controlled as Class C drugs in the U.K. An analytical database has been prepared to aid the detection and identification of controlled benzodiazepines. Chromatographic properties have been measured including gas chromatography (GC) retention index values, high-performance liquid chromatography (HPLC) capacity factors and thin-layer chromatography (TLC) RF x 100 values. UV spectroscopic and mass spectrometric (MS) data have also been recorded. Analytical data (GC, TLC and MS) are also presented for benzophenones which were produced by acid hydrolysis of the parent benzodiazepines.

Source: PubMed

Preferred by: David Osselton

Collection of analytical data for benzodiazepines and benzophenones.

Authors: Japp, M., Garthwaite, K., Geeson, A.V. and Osselton, M.D.

Journal: Journal of chromatography

Volume: 439

Issue: 2

Pages: 317-339

DOI: 10.1016/s0021-9673(01)83844-9

Abstract:

On April 1st, 1986, amendments were made to Schedule 2 to the Misuse of Drugs Act 1971 such that 33 benzodiazepines became controlled as Class C drugs in the U.K. An analytical database has been prepared to aid the detection and identification of controlled benzodiazepines. Chromatographic properties have been measured including gas chromatography (GC) retention index values, high-performance liquid chromatography (HPLC) capacity factors and thin-layer chromatography (TLC) RF x 100 values. UV spectroscopic and mass spectrometric (MS) data have also been recorded. Analytical data (GC, TLC and MS) are also presented for benzophenones which were produced by acid hydrolysis of the parent benzodiazepines.

Source: Europe PubMed Central