Influence of Caffeine on Heart Rate Variability in Patients with Long-Standing Type 1 Diabetes
Authors: Richardson, T., Rozkovec, A., Thomas, P., Ryder, J., Meckes, C. and Kerr, D.
Journal: Diabetes Care
Volume: 27
Issue: 5
Pages: 1127-1131
ISSN: 0149-5992
DOI: 10.2337/diacare.27.5.1127
Abstract:OBJECTIVE - The effect of caffeine on cardiovascular health remains controversial. Patients with long-standing type 1 diabetes are at risk of autonomic failure and sudden cardiac death. We investigated the effects of caffeine on autonomic dysfunction (as assessed by heart rate variability [HRV]) in this high-risk group and in a control population. RESEARCH DESIGN AND METHODS - Using a randomized blinded, placebo-controlled, crossover design trial, we examined 2 weeks of caffeine consumption (250 mg twice daily) on HRV in 20 type 1 diabetic patients and 10 matched healthy volunteers. RESULTS - Baseline HRV was blunted in the diabetic patients (P < 0.0005 vs. control subjects) and markedly increased by caffeine in both groups (+ 103% in the group with diabetes [P = 0.009] and +38% in control subjects [P = 0.002]). The caffeine-associated increase in HRV was not statistically different between the control and the type 1 diabetes groups (P = 0.16). CONCLUSIONS - Modest amounts of caffeine improved autonomic function in diabetic patients and healthy volunteers. For individuals with abnormal HRV, regular caffeine use may have the potential to reduce the risk of cardiovascular events.
Source: Scopus
Influence of caffeine on heart rate variability in patients with long-standing type 1 diabetes.
Authors: Richardson, T., Rozkovec, A., Thomas, P., Ryder, J., Meckes, C. and Kerr, D.
Journal: Diabetes Care
Volume: 27
Issue: 5
Pages: 1127-1131
ISSN: 0149-5992
DOI: 10.2337/diacare.27.5.1127
Abstract:OBJECTIVE: The effect of caffeine on cardiovascular health remains controversial. Patients with long-standing type 1 diabetes are at risk of autonomic failure and sudden cardiac death. We investigated the effects of caffeine on autonomic dysfunction (as assessed by heart rate variability [HRV]) in this high-risk group and in a control population. RESEARCH DESIGN AND METHODS: Using a randomized blinded, placebo-controlled, crossover design trial, we examined 2 weeks of caffeine consumption (250 mg twice daily) on HRV in 20 type 1 diabetic patients and 10 matched healthy volunteers. RESULTS: Baseline HRV was blunted in the diabetic patients (P < 0.0005 vs. control subjects) and markedly increased by caffeine in both groups (+103% in the group with diabetes [P = 0.009] and +38% in control subjects [P = 0.002]). The caffeine-associated increase in HRV was not statistically different between the control and the type 1 diabetes groups (P = 0.16). CONCLUSIONS: Modest amounts of caffeine improved autonomic function in diabetic patients and healthy volunteers. For individuals with abnormal HRV, regular caffeine use may have the potential to reduce the risk of cardiovascular events.
Source: PubMed
Influence of caffeine on heart rate variability in patients with Type 1 diabetes
Authors: Richardson, T.I.L., Ryder, J., Meckes, C., Rozkovec, A. and Kerr, D.
Journal: DIABETOLOGIA
Volume: 45
Pages: A336
ISSN: 0012-186X
Source: Web of Science (Lite)
Influence of caffeine on heart rate variability in patients with long-standing type 1 diabetes
Authors: Richardson, T., Rozkovec, A., Thomas, P., Ryder, J., Meckes, C. and Kerr, D.
Journal: Diabetes Care
Volume: 27
Pages: 1127-1131
ISSN: 0149-5992
Abstract:OBJECTIVE—The effect of caffeine on cardiovascular health remains controversial. Patients with long-standing type 1 diabetes are at risk of autonomic failure and sudden cardiac death. We investigated the effects of caffeine on autonomic dysfunction (as assessed by heart rate variability [HRV]) in this high-risk group and in a control population.
RESEARCH DESIGN AND METHODS—Using a randomized blinded, placebo-controlled, crossover design trial, we examined 2 weeks of caffeine consumption (250 mg twice daily) on HRV in 20 type 1 diabetic patients and 10 matched healthy volunteers.
RESULTS—Baseline HRV was blunted in the diabetic patients (P < 0.0005 vs. control subjects) and markedly increased by caffeine in both groups (+103% in the group with diabetes [P = 0.009] and +38% in control subjects [P = 0.002]). The caffeine-associated increase in HRV was not statistically different between the control and the type 1 diabetes groups (P = 0.16).
CONCLUSIONS—Modest amounts of caffeine improved autonomic function in diabetic patients and healthy volunteers. For individuals with abnormal HRV, regular caffeine use may have the potential to reduce the risk of cardiovascular events.
http://care.diabetesjournals.org/cgi/content/abstract/27/5/1127
Source: Manual
Preferred by: David Kerr
Influence of caffeine on heart rate variability in patients with long-standing type 1 diabetes.
Authors: Richardson, T., Rozkovec, A., Thomas, P., Ryder, J., Meckes, C. and Kerr, D.
Journal: Diabetes care
Volume: 27
Issue: 5
Pages: 1127-1131
eISSN: 1935-5548
ISSN: 0149-5992
DOI: 10.2337/diacare.27.5.1127
Abstract:Objective
The effect of caffeine on cardiovascular health remains controversial. Patients with long-standing type 1 diabetes are at risk of autonomic failure and sudden cardiac death. We investigated the effects of caffeine on autonomic dysfunction (as assessed by heart rate variability [HRV]) in this high-risk group and in a control population.Research design and methods
Using a randomized blinded, placebo-controlled, crossover design trial, we examined 2 weeks of caffeine consumption (250 mg twice daily) on HRV in 20 type 1 diabetic patients and 10 matched healthy volunteers.Results
Baseline HRV was blunted in the diabetic patients (P < 0.0005 vs. control subjects) and markedly increased by caffeine in both groups (+103% in the group with diabetes [P = 0.009] and +38% in control subjects [P = 0.002]). The caffeine-associated increase in HRV was not statistically different between the control and the type 1 diabetes groups (P = 0.16).Conclusions
Modest amounts of caffeine improved autonomic function in diabetic patients and healthy volunteers. For individuals with abnormal HRV, regular caffeine use may have the potential to reduce the risk of cardiovascular events.Source: Europe PubMed Central