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Toxicity of Titanium Dioxide Nanoparticles and Oxidative Stress

Authors: Wani, M.R. and Shadab, G.G.H.A.

Pages: 131-148

DOI: 10.1007/978-3-030-83446-3_6

Abstract:

Titanium dioxide nanoparticles (TiO2 NPs) are being used in food and other commonly used products on a large scale. As such, exposure to humans and environment has raised concerns regarding their toxic potential. Studies have reported that upon exposure to humans, TiO2 NPs accumulate and induce oxidative damage, genotoxicity, and apoptosis in lungs, alimentary tract, liver, heart, spleen, kidneys, and cardiac muscle and these tissues. In this chapter, we highlight various applications of TiO2 NPs, their toxicity potential as reported in published literature, and discuss their mechanism of toxicity.

Source: Scopus