One year follow-up of a pragmatic multi-centre randomised controlled trial of a group-based fatigue management programme (FACETS) for people with multiple sclerosis
Authors: Thomas, P.W., Thomas, S., Kersten, P., Jones, R., Slingsby, V., Nock, A., Davies Smith, A., Baker, R., Galvin, K.T. and Hillier, C.
Journal: BMC Neurology
Volume: 14
Issue: 1
eISSN: 1471-2377
DOI: 10.1186/1471-2377-14-109
Abstract:Background: Fatigue is one of the most common and debilitating symptoms of multiple sclerosis (MS). The aim was to evaluate the effectiveness at 1-year follow-up of a manualised group-based programme ('FACETS') for managing MS-fatigue.Methods: One-year follow-up of a pragmatic multi-centre randomised controlled trial. People with MS and significant fatigue were randomised to FACETS plus current local practice (FACETS) or current local practice alone (CLP), using concealed computer-generated randomisation. Participant blinding was not possible. Primary outcome measures were fatigue severity (Global Fatigue Severity subscale of the Fatigue Assessment Instrument), self-efficacy (MS-Fatigue Self-Efficacy) and disease-specific quality of life (MS Impact Scale).Results: Between May 2008 and November 2009, 164 participants were randomised. Primary outcome data were available at 1 year for 131 (80%). The benefits demonstrated at 4-months in the FACETS arm for fatigue severity and self-efficacy largely persisted, with a slight reduction in standardised effect sizes (SES) (-0.29, p = 0.06 and 0.34, p = 0.09, respectively). There was a significant difference on the MS Impact Scale favouring FACETS that had not been present at 4-months (SES -0.24, p = 0.046). No adverse events were reported.Conclusions: Improvements in fatigue severity and self-efficacy at 4-months follow-up following attendance of FACETS were mostly sustained at 1 year with additional improvements in MS impact. The FACETS programme provides modest long-term benefits to people with MS-fatigue.Trial registration: ISRCTN76517470. © 2014 Thomas et al.
https://eprints.bournemouth.ac.uk/22218/
Source: Scopus
One year follow-up of a pragmatic multi-centre randomised controlled trial of a group-based fatigue management programme (FACETS) for people with multiple sclerosis.
Authors: Thomas, P.W., Thomas, S., Kersten, P., Jones, R., Slingsby, V., Nock, A., Davies Smith, A., Baker, R., Galvin, K.T. and Hillier, C.
Journal: BMC Neurol
Volume: 14
Pages: 109
eISSN: 1471-2377
DOI: 10.1186/1471-2377-14-109
Abstract:BACKGROUND: Fatigue is one of the most common and debilitating symptoms of multiple sclerosis (MS). The aim was to evaluate the effectiveness at 1-year follow-up of a manualised group-based programme ('FACETS') for managing MS-fatigue. METHODS: One-year follow-up of a pragmatic multi-centre randomised controlled trial. People with MS and significant fatigue were randomised to FACETS plus current local practice (FACETS) or current local practice alone (CLP), using concealed computer-generated randomisation. Participant blinding was not possible. Primary outcome measures were fatigue severity (Global Fatigue Severity subscale of the Fatigue Assessment Instrument), self-efficacy (MS-Fatigue Self-Efficacy) and disease-specific quality of life (MS Impact Scale). RESULTS: Between May 2008 and November 2009, 164 participants were randomised. Primary outcome data were available at 1 year for 131 (80%). The benefits demonstrated at 4-months in the FACETS arm for fatigue severity and self-efficacy largely persisted, with a slight reduction in standardised effect sizes (SES) (-0.29, p = 0.06 and 0.34, p = 0.09, respectively). There was a significant difference on the MS Impact Scale favouring FACETS that had not been present at 4-months (SES -0.24, p = 0.046). No adverse events were reported. CONCLUSIONS: Improvements in fatigue severity and self-efficacy at 4-months follow-up following attendance of FACETS were mostly sustained at 1 year with additional improvements in MS impact. The FACETS programme provides modest long-term benefits to people with MS-fatigue. TRIAL REGISTRATION: ISRCTN76517470.
https://eprints.bournemouth.ac.uk/22218/
Source: PubMed
Preferred by: Paula Kersten and Sarah Thomas
One year follow-up of a pragmatic multi-centre randomised controlled trial of a group-based fatigue management programme (FACETS) for people with multiple sclerosis
Authors: Thomas, P.W., Thomas, S., Kersten, P., Jones, R., Slingsby, V., Nock, A., Smith, A.D., Baker, R., Galvin, K.T. and Hillier, C.
Journal: BMC NEUROLOGY
Volume: 14
ISSN: 1471-2377
DOI: 10.1186/1471-2377-14-109
https://eprints.bournemouth.ac.uk/22218/
Source: Web of Science (Lite)
One year follow-up of a pragmatic multi-centre randomised controlled trial of a group-based fatigue management programme (FACETS) for people with multiple sclerosis.
Authors: Thomas, P.W., Thomas, S., Kersten, P., Jones, R., Slingsby, V., Nock, A., Davies Smith, A., Baker, R., Galvin, K.T. and Hillier, C.
Journal: BMC neurology
Volume: 14
Pages: 109
eISSN: 1471-2377
ISSN: 1471-2377
DOI: 10.1186/1471-2377-14-109
Abstract:Background
Fatigue is one of the most common and debilitating symptoms of multiple sclerosis (MS). The aim was to evaluate the effectiveness at 1-year follow-up of a manualised group-based programme ('FACETS') for managing MS-fatigue.Methods
One-year follow-up of a pragmatic multi-centre randomised controlled trial. People with MS and significant fatigue were randomised to FACETS plus current local practice (FACETS) or current local practice alone (CLP), using concealed computer-generated randomisation. Participant blinding was not possible. Primary outcome measures were fatigue severity (Global Fatigue Severity subscale of the Fatigue Assessment Instrument), self-efficacy (MS-Fatigue Self-Efficacy) and disease-specific quality of life (MS Impact Scale).Results
Between May 2008 and November 2009, 164 participants were randomised. Primary outcome data were available at 1 year for 131 (80%). The benefits demonstrated at 4-months in the FACETS arm for fatigue severity and self-efficacy largely persisted, with a slight reduction in standardised effect sizes (SES) (-0.29, p = 0.06 and 0.34, p = 0.09, respectively). There was a significant difference on the MS Impact Scale favouring FACETS that had not been present at 4-months (SES -0.24, p = 0.046). No adverse events were reported.Conclusions
Improvements in fatigue severity and self-efficacy at 4-months follow-up following attendance of FACETS were mostly sustained at 1 year with additional improvements in MS impact. The FACETS programme provides modest long-term benefits to people with MS-fatigue.Trial registration
ISRCTN76517470.https://eprints.bournemouth.ac.uk/22218/
Source: Europe PubMed Central
One year follow-up of a pragmatic multi-centre randomised controlled trial of a group-based fatigue management programme (FACETS) for people with multiple sclerosis.
Authors: Thomas, P., Thomas, S., Kersten, P., Jones, R., Slingsby, V., Nock, A., Davies Smith, A., Baker, R., Galvin, K.T. and Hillier, C.
Journal: BMC Neurology
Volume: 14
Pages: 109
ISSN: 1471-2377
Abstract:Fatigue is one of the most common and debilitating symptoms of multiple sclerosis (MS). The aim was to evaluate the effectiveness at 1-year follow-up of a manualised group-based programme ('FACETS') for managing MS-fatigue.
https://eprints.bournemouth.ac.uk/22218/
Source: BURO EPrints