Photoprotection of Parenteral Nutrition Enhances Advancement of Minimal Enteral Nutrition in Preterm Infants

Authors: Khashu, M., Harrison, A., Lalari, V., Gow, A., Lavoie, J.C. and Chessex, P.

Journal: Seminars in Perinatology

Volume: 30

Issue: 3

Pages: 139-145

ISSN: 0146-0005

DOI: 10.1053/j.semperi.2006.04.007

Abstract:

Background: Light exposure of TPN generates peroxides which induce vasoconstriction. Mesenteric vasoconstriction may affect feeding tolerance. Since photo-protection of TPN decreases peroxide generation, we hypothesized that shielding TPN from light may improve the establishment of minimal enteral nutrition in preterm infants. Methods: Infants were randomized to TPN being light exposed (LE) or protected (LP) from birth. Feeding volumes were monitored through 7 days of life in those initiated on minimal enteral nutrition (MEN). Comparisons between LP and LE were performed by ANOVA. Results: Daily increments and cumulative volumes of enteral feeds (mL/kg birth weight/d) during the first week of life were significantly higher in LP (n = 18) than LE (n = 19). Conclusion: Photo-protection of parenteral nutrition enhances advancement of MEN in preterm infants. Further research is needed to substantiate these findings and determine whether this confers long-term nutritional advantages. © 2006 Elsevier Inc. All rights reserved.

Source: Scopus

Photoprotection of parenteral nutrition enhances advancement of minimal enteral nutrition in preterm infants.

Authors: Khashu, M., Harrison, A., Lalari, V., Gow, A., Lavoie, J.-C. and Chessex, P.

Journal: Semin Perinatol

Volume: 30

Issue: 3

Pages: 139-145

ISSN: 0146-0005

DOI: 10.1053/j.semperi.2006.04.007

Abstract:

BACKGROUND: Light exposure of TPN generates peroxides which induce vasoconstriction. Mesenteric vasoconstriction may affect feeding tolerance. Since photo-protection of TPN decreases peroxide generation, we hypothesized that shielding TPN from light may improve the establishment of minimal enteral nutrition in preterm infants. METHODS: Infants were randomized to TPN being light exposed (LE) or protected (LP) from birth. Feeding volumes were monitored through 7 days of life in those initiated on minimal enteral nutrition (MEN). Comparisons between LP and LE were performed by ANOVA. RESULTS: Daily increments and cumulative volumes of enteral feeds (mL/kg birth weight/d) during the first week of life were significantly higher in LP (n = 18) than LE (n = 19). CONCLUSION: Photo-protection of parenteral nutrition enhances advancement of MEN in preterm infants. Further research is needed to substantiate these findings and determine whether this confers long-term nutritional advantages.

Source: PubMed

Preferred by: Minesh Khashu

Photoprotection of parenteral nutrition enhances advancement of minimal enteral nutrition in preterm infants

Authors: Khashu, M., Harrison, A., Lalari, V., Gow, A., Lavoie, J.-C. and Chessex, P.

Journal: SEMINARS IN PERINATOLOGY

Volume: 30

Issue: 3

Pages: 139-145

eISSN: 1558-075X

ISSN: 0146-0005

DOI: 10.1053/j.semperi.2006.04.007

Source: Web of Science (Lite)

Photoprotection of parenteral nutrition enhances advancement of minimal enteral nutrition in preterm infants.

Authors: Khashu, M., Harrison, A., Lalari, V., Gow, A., Lavoie, J.-C. and Chessex, P.

Journal: Seminars in perinatology

Volume: 30

Issue: 3

Pages: 139-145

eISSN: 1558-075X

ISSN: 0146-0005

DOI: 10.1053/j.semperi.2006.04.007

Abstract:

Background

Light exposure of TPN generates peroxides which induce vasoconstriction. Mesenteric vasoconstriction may affect feeding tolerance. Since photo-protection of TPN decreases peroxide generation, we hypothesized that shielding TPN from light may improve the establishment of minimal enteral nutrition in preterm infants.

Methods

Infants were randomized to TPN being light exposed (LE) or protected (LP) from birth. Feeding volumes were monitored through 7 days of life in those initiated on minimal enteral nutrition (MEN). Comparisons between LP and LE were performed by ANOVA.

Results

Daily increments and cumulative volumes of enteral feeds (mL/kg birth weight/d) during the first week of life were significantly higher in LP (n = 18) than LE (n = 19).

Conclusion

Photo-protection of parenteral nutrition enhances advancement of MEN in preterm infants. Further research is needed to substantiate these findings and determine whether this confers long-term nutritional advantages.

Source: Europe PubMed Central