HbA<inf>1c</inf> 3months after diagnosis predicts premature mortality in patients with new onset type 2 diabetes
Authors: Kerr, D., Partridge, H., Knott, J. and Thomas, P.W.
Journal: Diabetic Medicine
Volume: 28
Issue: 12
Pages: 1520-1524
eISSN: 1464-5491
ISSN: 0742-3071
DOI: 10.1111/j.1464-5491.2011.03443.x
Abstract:Aims To determine 5-year mortality rates, following the diagnosis of Type 2 diabetes, in a large local cohort of individuals with new onset of Type 2 diabetes seen within a few weeks of diagnosis in a single, community-based education programme. Methods We reviewed referrals for people with Type 2 diabetes to our service over 5years from 1999 to 2003 and determined, via regression analysis, which factors contributed significantly to mortality rates up to the end of 2007. Results A total of 3781 new referrals were reviewed with an approximate doubling of referral rates over 5years (546 in 1999-997 in 2003). Although the number of people developing the condition has increased, mortality rates over the 5years from diagnosis has fallen from 11% in 1999-9% in 2003 (P<0.005) Age at diagnosis was the strongest predictor of mortality (P<0.001) but HbA1c at 3months after diagnosis (P<0.001), systolic (P<0.001) and diastolic (P=0.05) blood pressure, smoking status (P<0.001) and gender (P=0.04) were also significant predictors. Conclusions Our retrospective analysis adds weight to evidence suggesting that referral rates for people with Type 2 diabetes are increasing rapidly and that mortality rates are reducing but that the reasons for this are multifactorial. In addition to blood pressure, smoking and gender, the HbA1c achieved 3months after the initial diagnosis also appears to predict subsequent mortality. It may be appropriate to consider early and intensive intervention for individuals with new onset type 2 diabetes. © 2011 The Author. Diabetic Medicine © 2011 Diabetes UK.
Source: Scopus
HbA1c 3 months after diagnosis predicts premature mortality in patients with new onset type 2 diabetes.
Authors: Kerr, D., Partridge, H., Knott, J. and Thomas, P.W.
Journal: Diabet Med
Volume: 28
Issue: 12
Pages: 1520-1524
eISSN: 1464-5491
DOI: 10.1111/j.1464-5491.2011.03443.x
Abstract:AIMS: To determine 5-year mortality rates, following the diagnosis of Type 2 diabetes, in a large local cohort of individuals with new onset of Type 2 diabetes seen within a few weeks of diagnosis in a single, community-based education programme. METHODS: We reviewed referrals for people with Type 2 diabetes to our service over 5 years from 1999 to 2003 and determined, via regression analysis, which factors contributed significantly to mortality rates up to the end of 2007. RESULTS: A total of 3781 new referrals were reviewed with an approximate doubling of referral rates over 5 years (546 in 1999-997 in 2003). Although the number of people developing the condition has increased, mortality rates over the 5 years from diagnosis has fallen from 11% in 1999-9% in 2003 (P < 0.005) Age at diagnosis was the strongest predictor of mortality (P < 0.001) but HbA(1c) at 3 months after diagnosis (P < 0.001), systolic (P < 0.001) and diastolic (P = 0.05) blood pressure, smoking status (P < 0.001) and gender (P = 0.04) were also significant predictors. CONCLUSIONS: Our retrospective analysis adds weight to evidence suggesting that referral rates for people with Type 2 diabetes are increasing rapidly and that mortality rates are reducing but that the reasons for this are multifactorial. In addition to blood pressure, smoking and gender, the HbA(1c) achieved 3 months after the initial diagnosis also appears to predict subsequent mortality. It may be appropriate to consider early and intensive intervention for individuals with new onset type 2 diabetes.
Source: PubMed
Preferred by: David Kerr
HbA1c 3 months after diagnosis predicts premature mortality in patients with new onset type 2 diabetes
Authors: Kerr, D., Partridge, H., Knott, J. and Thomas, P.W.
Journal: DIABETIC MEDICINE
Volume: 28
Issue: 12
Pages: 1520-1524
eISSN: 1464-5491
ISSN: 0742-3071
DOI: 10.1111/j.1464-5491.2011.03443.x
Source: Web of Science (Lite)
HbA1c 3 months after diagnosis predicts premature mortality in patients with new onset type 2 diabetes.
Authors: Kerr, D., Partridge, H., Knott, J. and Thomas, P.W.
Journal: Diabetic medicine : a journal of the British Diabetic Association
Volume: 28
Issue: 12
Pages: 1520-1524
eISSN: 1464-5491
ISSN: 0742-3071
DOI: 10.1111/j.1464-5491.2011.03443.x
Abstract:Aims
To determine 5-year mortality rates, following the diagnosis of Type 2 diabetes, in a large local cohort of individuals with new onset of Type 2 diabetes seen within a few weeks of diagnosis in a single, community-based education programme.Methods
We reviewed referrals for people with Type 2 diabetes to our service over 5 years from 1999 to 2003 and determined, via regression analysis, which factors contributed significantly to mortality rates up to the end of 2007.Results
A total of 3781 new referrals were reviewed with an approximate doubling of referral rates over 5 years (546 in 1999-997 in 2003). Although the number of people developing the condition has increased, mortality rates over the 5 years from diagnosis has fallen from 11% in 1999-9% in 2003 (P < 0.005) Age at diagnosis was the strongest predictor of mortality (P < 0.001) but HbA(1c) at 3 months after diagnosis (P < 0.001), systolic (P < 0.001) and diastolic (P = 0.05) blood pressure, smoking status (P < 0.001) and gender (P = 0.04) were also significant predictors.Conclusions
Our retrospective analysis adds weight to evidence suggesting that referral rates for people with Type 2 diabetes are increasing rapidly and that mortality rates are reducing but that the reasons for this are multifactorial. In addition to blood pressure, smoking and gender, the HbA(1c) achieved 3 months after the initial diagnosis also appears to predict subsequent mortality. It may be appropriate to consider early and intensive intervention for individuals with new onset type 2 diabetes.Source: Europe PubMed Central