POLYMERASE CHAIN REACTION FOR DETECTION OF DISSEMINATION IN GASTRIC LYMPHOMA
Authors: Cunningham, D., Rosin, R.D., Baron, J.H., Hickish, T., Sauven, P., Farrell, P.T. and Isaacson, P.
Journal: The Lancet
Volume: 333
Issue: 8640
Pages: 695-697
ISSN: 0140-6736
DOI: 10.1016/S0140-6736(89)92208-3
Abstract:The polymerase chain reaction (PCR) was used to detect malignant lymphoma cells with the bcl-2 gene rearrangement in the peritoneal washings and bone marrow of a patient with an apparently localised gastric lymphoma. After four courses of cytotoxic drug treatment the cells could no longer be detected in either site. PCR is a useful addition to the staging investigations of non-Hodgkin lymphoma and can also be used to monitor response to treatment. © 1989.
Source: Scopus