Neandertal and Denisovan DNA from Pleistocene sediments
Authors: Slon, V., Hopfe, C., Weiß, C.L., Mafessoni, F., De La Rasilla, M., Lalueza-Fox, C., Rosas, A., Soressi, M., Knul, M.V., Miller, R., Stewart, J.R., Derevianko, A.P., Jacobs, Z., Li, B., Roberts, R.G., Shunkov, M.V., De Lumley, H., Perrenoud, C., Gušić, I., Kućan, Ž., Rudan, P., Aximu-Petri, A., Essel, E., Nagel, S., Nickel, B., Schmidt, A., Prüfer, K., Kelso, J., Burbano, H.A., Pääbo, S., Meyer, M.
Journal: Science
Publication Date: 12/05/2017
Volume: 356
Issue: 6338
Pages: 605-608
eISSN: 1095-9203
ISSN: 0036-8075
DOI: 10.1126/science.aam9695
Abstract:Although a rich record of Pleistocene human-associated archaeological assemblages exists, the scarcity of hominin fossils often impedes the understanding of which hominins occupied a site. Using targeted enrichment of mitochondrial DNA, we show that cave sediments represent a rich source of ancient mammalian DNA that often includes traces of hominin DNA, even at sites and in layers where no hominin remains have been discovered. By automation-assisted screening of numerous sediment samples, we detected Neandertal DNA in eight archaeological layers from four caves in Eurasia. In Denisova Cave, we retrieved Denisovan DNA in a Middle Pleistocene layer near the bottom of the stratigraphy. Our work opens the possibility of detecting the presence of hominin groups at sites and in areas where no skeletal remains are found.
https://eprints.bournemouth.ac.uk/29206/
Source: Scopus
Neandertal and Denisovan DNA from Pleistocene sediments.
Authors: Slon, V., Hopfe, C., Weiß, C.L., Mafessoni, F., de la Rasilla, M., Lalueza-Fox, C., Rosas, A., Soressi, M., Knul, M.V., Miller, R., Stewart, J.R., Derevianko, A.P., Jacobs, Z., Li, B., Roberts, R.G., Shunkov, M.V., de Lumley, H., Perrenoud, C., Gušić, I., Kućan, Ž., Rudan, P., Aximu-Petri, A., Essel, E., Nagel, S., Nickel, B., Schmidt, A., Prüfer, K., Kelso, J., Burbano, H.A., Pääbo, S., Meyer, M.
Journal: Science
Publication Date: 12/05/2017
Volume: 356
Issue: 6338
Pages: 605-608
eISSN: 1095-9203
DOI: 10.1126/science.aam9695
Abstract:Although a rich record of Pleistocene human-associated archaeological assemblages exists, the scarcity of hominin fossils often impedes the understanding of which hominins occupied a site. Using targeted enrichment of mitochondrial DNA, we show that cave sediments represent a rich source of ancient mammalian DNA that often includes traces of hominin DNA, even at sites and in layers where no hominin remains have been discovered. By automation-assisted screening of numerous sediment samples, we detected Neandertal DNA in eight archaeological layers from four caves in Eurasia. In Denisova Cave, we retrieved Denisovan DNA in a Middle Pleistocene layer near the bottom of the stratigraphy. Our work opens the possibility of detecting the presence of hominin groups at sites and in areas where no skeletal remains are found.
https://eprints.bournemouth.ac.uk/29206/
Source: PubMed
Neandertal and Denisovan DNA from Pleistocene sediments
Authors: Slon, V., Hopfe, C., Weiss, C.L., Mafessoni, F., de la Rasilla, M., Lalueza-Fox, C., Rosas, A., Soressi, M., Knul, M.V., Miller, R., Stewart, J.R., Derevianko, A.P., Jacobs, Z., Li, B., Roberts, R.G., Shunkov, M.V., de Lumley, H., Perrenoud, C., Gusic, I., Kucan, Z., Rudan, P., Aximu-Petri, A., Essel, E., Nagel, S., Nickel, B., Schmidt, A., Pruefer, K., Kelso, J., Burbano, H.A., Paeaebo, S., Meyer, M.
Journal: SCIENCE
Publication Date: 2017
Volume: 356
Issue: 6338
Pages: 605-+
eISSN: 1095-9203
ISSN: 0036-8075
DOI: 10.1126/science.aam9695
https://eprints.bournemouth.ac.uk/29206/
Source: Web of Science
Neandertal and Denisovan DNA from Pleistocene sediments.
Authors: Slon, V., Hopfe, C., Weiß, C.L., Mafessoni, F., de la Rasilla, M., Lalueza-Fox, C., Rosas, A., Soressi, M., Knul, M.V., Miller, R., Stewart, J.R., Derevianko, A.P., Jacobs, Z., Li, B., Roberts, R.G., Shunkov, M.V., de Lumley, H., Perrenoud, C., Gušić, I., Kućan, Ž., Rudan, P., Aximu-Petri, A., Essel, E., Nagel, S., Nickel, B., Schmidt, A., Prüfer, K., Kelso, J., Burbano, H.A., Pääbo, S., Meyer, M.
Journal: Science (New York, N.Y.)
Publication Date: 05/2017
Volume: 356
Issue: 6338
Pages: 605-608
eISSN: 1095-9203
ISSN: 0036-8075
DOI: 10.1126/science.aam9695
Abstract:Although a rich record of Pleistocene human-associated archaeological assemblages exists, the scarcity of hominin fossils often impedes the understanding of which hominins occupied a site. Using targeted enrichment of mitochondrial DNA, we show that cave sediments represent a rich source of ancient mammalian DNA that often includes traces of hominin DNA, even at sites and in layers where no hominin remains have been discovered. By automation-assisted screening of numerous sediment samples, we detected Neandertal DNA in eight archaeological layers from four caves in Eurasia. In Denisova Cave, we retrieved Denisovan DNA in a Middle Pleistocene layer near the bottom of the stratigraphy. Our work opens the possibility of detecting the presence of hominin groups at sites and in areas where no skeletal remains are found.
https://eprints.bournemouth.ac.uk/29206/
Source: Europe PubMed Central