The relation of structural integrity and task-related functional connectivity in the aging brain
Authors: Burianová, H., Marstaller, L., Choupan, J., Sepehrband, F., Ziaei, M. and Reutens, D.
Journal: Neurobiology of Aging
Volume: 36
Issue: 10
Pages: 2830-2837
eISSN: 1558-1497
ISSN: 0197-4580
DOI: 10.1016/j.neurobiolaging.2015.07.006
Abstract:The relations among structural integrity, functional connectivity (FC), and cognitive performance in the aging brain are still understudied. Here, we used multimodal and multivariate approaches to specifically examine age-related changes in task-related FC, gray-matter volumetrics, white-matter integrity, and performance. Our results are two-fold, showing (i) age-related differences in FC of the working memory network and (ii) age-related recruitment of a compensatory network associated with better accuracy on the task. Increased connectivity in the compensatory network correlates positively with preserved white-matter integrity in bilateral frontoparietal tracks and with larger gray-matter volume of right inferior parietal lobule. These findings demonstrate the importance of structural integrity and FC in working memory performance associated with healthy aging.
https://eprints.bournemouth.ac.uk/35327/
Source: Scopus
The relation of structural integrity and task-related functional connectivity in the aging brain.
Authors: Burianová, H., Marstaller, L., Choupan, J., Sepehrband, F., Ziaei, M. and Reutens, D.
Journal: Neurobiol Aging
Volume: 36
Issue: 10
Pages: 2830-2837
eISSN: 1558-1497
DOI: 10.1016/j.neurobiolaging.2015.07.006
Abstract:The relations among structural integrity, functional connectivity (FC), and cognitive performance in the aging brain are still understudied. Here, we used multimodal and multivariate approaches to specifically examine age-related changes in task-related FC, gray-matter volumetrics, white-matter integrity, and performance. Our results are two-fold, showing (i) age-related differences in FC of the working memory network and (ii) age-related recruitment of a compensatory network associated with better accuracy on the task. Increased connectivity in the compensatory network correlates positively with preserved white-matter integrity in bilateral frontoparietal tracks and with larger gray-matter volume of right inferior parietal lobule. These findings demonstrate the importance of structural integrity and FC in working memory performance associated with healthy aging.
https://eprints.bournemouth.ac.uk/35327/
Source: PubMed
The relation of structural integrity and task-related functional connectivity in the aging brain
Authors: Burianova, H., Marstaller, L., Choupan, J., Sepehrband, F., Ziaei, M. and Reutens, D.
Journal: NEUROBIOLOGY OF AGING
Volume: 36
Issue: 10
Pages: 2830-2837
eISSN: 1558-1497
ISSN: 0197-4580
DOI: 10.1016/j.neurobiolaging.2015.07.006
https://eprints.bournemouth.ac.uk/35327/
Source: Web of Science (Lite)
The relation of structural integrity and task-related functional connectivity in the aging brain.
Authors: Burianová, H., Marstaller, L., Choupan, J., Sepehrband, F., Ziaei, M. and Reutens, D.
Journal: Neurobiology of aging
Volume: 36
Issue: 10
Pages: 2830-2837
eISSN: 1558-1497
ISSN: 0197-4580
DOI: 10.1016/j.neurobiolaging.2015.07.006
Abstract:The relations among structural integrity, functional connectivity (FC), and cognitive performance in the aging brain are still understudied. Here, we used multimodal and multivariate approaches to specifically examine age-related changes in task-related FC, gray-matter volumetrics, white-matter integrity, and performance. Our results are two-fold, showing (i) age-related differences in FC of the working memory network and (ii) age-related recruitment of a compensatory network associated with better accuracy on the task. Increased connectivity in the compensatory network correlates positively with preserved white-matter integrity in bilateral frontoparietal tracks and with larger gray-matter volume of right inferior parietal lobule. These findings demonstrate the importance of structural integrity and FC in working memory performance associated with healthy aging.
https://eprints.bournemouth.ac.uk/35327/
Source: Europe PubMed Central
The relation of structural integrity and task-related functional connectivity in the aging brain.
Authors: Burianová, H., Marstaller, L., Choupan, J., Sepehrband, F., Ziaei, M. and Reutens, D.
Journal: Neurobiology of Aging
Volume: 36
Issue: 10
Pages: 2830-2837
ISSN: 0197-4580
Abstract:The relations among structural integrity, functional connectivity (FC), and cognitive performance in the aging brain are still understudied. Here, we used multimodal and multivariate approaches to specifically examine age-related changes in task-related FC, gray-matter volumetrics, white-matter integrity, and performance. Our results are two-fold, showing (i) age-related differences in FC of the working memory network and (ii) age-related recruitment of a compensatory network associated with better accuracy on the task. Increased connectivity in the compensatory network correlates positively with preserved white-matter integrity in bilateral frontoparietal tracks and with larger gray-matter volume of right inferior parietal lobule. These findings demonstrate the importance of structural integrity and FC in working memory performance associated with healthy aging.
https://eprints.bournemouth.ac.uk/35327/
Source: BURO EPrints