An in vivo study exploring correlations between early-to-moderate disc degeneration and flexion mobility in the lumbar spine

Authors: Breen, A., Mellor, F., Morris, A. and Breen, A.

Journal: European Spine Journal

Volume: 29

Issue: 10

Pages: 2619-2627

eISSN: 1432-0932

ISSN: 0940-6719

DOI: 10.1007/s00586-020-06526-0

Abstract:

Purpose: Early disc degeneration (DD) has been thought to be associated with loss of spine stability. However, before this can be understood in relation to back pain, it is necessary to know the relationship between DD and intervertebral motion in people without pain. This study aimed to find out if early-to-moderate DD is associated with intervertebral motion in people without back pain. Methods: Ten pain-free adults, aged 51–71, received recumbent and weight bearing MRI scans and quantitative fluoroscopy (QF) screenings during recumbent and upright lumbar flexion. Forty individual level and 10 composite (L2-S1) radiographic and MRI DD gradings were recorded and correlated with intervertebral flexion ROM, translation, laxity and motion sharing inequality and variability for both positions. Results: Kinematic values were similar to previous control studies. DD was evidenced up to moderate levels by both radiographic and MRI grading. Disc height loss correlated slightly, but negatively with flexion during weight bearing flexion (R = − 0.356, p = 0.0.025). Composite MRI DD and T2 signal loss evidenced similar relationships (R = − 0.305, R = − 0.267) but did not reach statistical significance (p = 0.056, p = 0.096). No significant relationships between any other kinematic variables and DD were found. Conclusion: This study found only small, indefinite associations between early-to-moderate DD and intervertebral motion in healthy controls. Motion sharing in the absence of pain was also not related to early DD, consistent with previous control studies. Further research is needed to investigate these relationships in patients.

https://eprints.bournemouth.ac.uk/34227/

Source: Scopus

An in vivo study exploring correlations between early-to-moderate disc degeneration and flexion mobility in the lumbar spine.

Authors: Breen, A., Mellor, F., Morris, A. and Breen, A.

Journal: Eur Spine J

Volume: 29

Issue: 10

Pages: 2619-2627

eISSN: 1432-0932

DOI: 10.1007/s00586-020-06526-0

Abstract:

PURPOSE: Early disc degeneration (DD) has been thought to be associated with loss of spine stability. However, before this can be understood in relation to back pain, it is necessary to know the relationship between DD and intervertebral motion in people without pain. This study aimed to find out if early-to-moderate DD is associated with intervertebral motion in people without back pain. METHODS: Ten pain-free adults, aged 51-71, received recumbent and weight bearing MRI scans and quantitative fluoroscopy (QF) screenings during recumbent and upright lumbar flexion. Forty individual level and 10 composite (L2-S1) radiographic and MRI DD gradings were recorded and correlated with intervertebral flexion ROM, translation, laxity and motion sharing inequality and variability for both positions. RESULTS: Kinematic values were similar to previous control studies. DD was evidenced up to moderate levels by both radiographic and MRI grading. Disc height loss correlated slightly, but negatively with flexion during weight bearing flexion (R =  - 0.356, p = 0.0.025). Composite MRI DD and T2 signal loss evidenced similar relationships (R =  - 0.305, R =  - 0.267) but did not reach statistical significance (p = 0.056, p = 0.096). No significant relationships between any other kinematic variables and DD were found. CONCLUSION: This study found only small, indefinite associations between early-to-moderate DD and intervertebral motion in healthy controls. Motion sharing in the absence of pain was also not related to early DD, consistent with previous control studies. Further research is needed to investigate these relationships in patients.

https://eprints.bournemouth.ac.uk/34227/

Source: PubMed

An in vivo study exploring correlations between early-to-moderate disc degeneration and flexion mobility in the lumbar spine

Authors: Breen, A., Mellor, F., Morris, A. and Breen, A.

Journal: EUROPEAN SPINE JOURNAL

Volume: 29

Issue: 10

Pages: 2619-2627

eISSN: 1432-0932

ISSN: 0940-6719

DOI: 10.1007/s00586-020-06526-0

https://eprints.bournemouth.ac.uk/34227/

Source: Web of Science (Lite)

An in-vivo study exploring correlations between early-to-moderate disc degeneration and flexion mobility in the lumbar spine

Authors: Breen, A., Mellor, F., Morris, A. and Breen, A.

Journal: European Spine Journal

Publisher: Springer Nature

ISSN: 0940-6719

Abstract:

Purpose: Early disc degeneration (DD) has been thought to be associated with loss of spine 6 stability. However, before this can be understood in relation to back pain, it is necessary to 7 know the relationship between DD and intervertebral motion in people without pain. This 8 study aimed to find out if early to moderate DD is associated with intervertebral motion in 9 people without back pain.

10 Methods: Ten pain free adults, aged 51-71 received recumbent and weight bearing MRI 11 scans and quantitative fluoroscopy (QF) screenings during recumbent and upright lumbar 12 flexion. Forty individual level and 10 composite (L2-S1) radiographic and MRI DD gradings 13 were recorded and correlated with intervertebral flexion ROM, translation, laxity, and 14 motion sharing inequality and variability for both positions.

15 Results: Kinematic values were similar to previous control studies. DD was evidenced up to 16 moderate levels by both radiographic and MRI grading. Disc height loss correlated slightly, 17 but negatively with flexion during weight bearing flexion (R=-0.356, p=0.0.025). Composite 18 MRI DD and T2 signal loss evidenced similar relationships (R= -0.305, R= -0.267) but did not 19 reach statistical significance (p=0.056, p=0.096). No significant relationships between any 20 other kinematic variables and DD were found.

21 Conclusion: This study found only small, indefinite associations between early-to-moderate 22 DD and intervertebral motion in healthy controls. Motion sharing in the absence of pain 23 was also not related to early DD, consistent with previous control studies. Further research 24 is needed to investigate these relationships in patients.

25 Key words: back pain, disc degeneration, instability, imaging

https://eprints.bournemouth.ac.uk/34227/

Source: Manual

An in vivo study exploring correlations between early-to-moderate disc degeneration and flexion mobility in the lumbar spine.

Authors: Breen, A., Mellor, F., Morris, A. and Breen, A.

Journal: European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society

Volume: 29

Issue: 10

Pages: 2619-2627

eISSN: 1432-0932

ISSN: 0940-6719

DOI: 10.1007/s00586-020-06526-0

Abstract:

Purpose

Early disc degeneration (DD) has been thought to be associated with loss of spine stability. However, before this can be understood in relation to back pain, it is necessary to know the relationship between DD and intervertebral motion in people without pain. This study aimed to find out if early-to-moderate DD is associated with intervertebral motion in people without back pain.

Methods

Ten pain-free adults, aged 51-71, received recumbent and weight bearing MRI scans and quantitative fluoroscopy (QF) screenings during recumbent and upright lumbar flexion. Forty individual level and 10 composite (L2-S1) radiographic and MRI DD gradings were recorded and correlated with intervertebral flexion ROM, translation, laxity and motion sharing inequality and variability for both positions.

Results

Kinematic values were similar to previous control studies. DD was evidenced up to moderate levels by both radiographic and MRI grading. Disc height loss correlated slightly, but negatively with flexion during weight bearing flexion (R =  - 0.356, p = 0.0.025). Composite MRI DD and T2 signal loss evidenced similar relationships (R =  - 0.305, R =  - 0.267) but did not reach statistical significance (p = 0.056, p = 0.096). No significant relationships between any other kinematic variables and DD were found.

Conclusion

This study found only small, indefinite associations between early-to-moderate DD and intervertebral motion in healthy controls. Motion sharing in the absence of pain was also not related to early DD, consistent with previous control studies. Further research is needed to investigate these relationships in patients.

https://eprints.bournemouth.ac.uk/34227/

Source: Europe PubMed Central

An in-vivo study exploring correlations between early-to-moderate disc degeneration and flexion mobility in the lumbar spine

Authors: Breen, A.C., Mellor, F., Morris, A. and Breen, A.

Journal: European Spine Journal

Volume: 29

Pages: 2619-2627

ISSN: 0940-6719

Abstract:

Purpose: Early disc degeneration (DD) has been thought to be associated with loss of spine 6 stability. However, before this can be understood in relation to back pain, it is necessary to 7 know the relationship between DD and intervertebral motion in people without pain. This 8 study aimed to find out if early to moderate DD is associated with intervertebral motion in 9 people without back pain. 10 Methods: Ten pain free adults, aged 51-71 received recumbent and weight bearing MRI 11 scans and quantitative fluoroscopy (QF) screenings during recumbent and upright lumbar 12 flexion. Forty individual level and 10 composite (L2-S1) radiographic and MRI DD gradings 13 were recorded and correlated with intervertebral flexion ROM, translation, laxity, and 14 motion sharing inequality and variability for both positions. 15 Results: Kinematic values were similar to previous control studies. DD was evidenced up to 16 moderate levels by both radiographic and MRI grading. Disc height loss correlated slightly, 17 but negatively with flexion during weight bearing flexion (R=-0.356, p=0.0.025). Composite 18 MRI DD and T2 signal loss evidenced similar relationships (R= -0.305, R= -0.267) but did not 19 reach statistical significance (p=0.056, p=0.096). No significant relationships between any 20 other kinematic variables and DD were found. 21 Conclusion: This study found only small, indefinite associations between early-to-moderate 22 DD and intervertebral motion in healthy controls. Motion sharing in the absence of pain 23 was also not related to early DD, consistent with previous control studies. Further research 24 is needed to investigate these relationships in patients. 25 Key words: back pain, disc degeneration, instability, imaging

https://eprints.bournemouth.ac.uk/34227/

Source: BURO EPrints