Sensory gating is related to positive and disorganised schizotypy in contrast to smooth pursuit eye movements and latent inhibition
Authors: Hills, P.J., Vasilev, M.R., Ford, P., Snell, L., Whitworth, E., Parsons, T., Morisson, R., Silveira, A. and Angele, B.
Journal: Neuropsychologia
Volume: 161
eISSN: 1873-3514
ISSN: 0028-3932
DOI: 10.1016/j.neuropsychologia.2021.107989
Abstract:Since the characteristics and symptoms of both schizophrenia and schizotypy are manifested heterogeneously, it is possible that different endophenotypes and neurophysiological measures (sensory gating and smooth pursuit eye movement errors) represent different clusters of symptoms. Participants (N = 205) underwent a standard conditioned-pairing paradigm to establish their sensory gating ratio, a smooth-pursuit eye-movement task, a latent inhibition task, and completed the Schizotypal Personality Questionnaire. A Multidimensional Scaling analysis revealed that sensory gating was related to positive and disorganised dimensions of schizotypy. Latent inhibition and prepulse inhibition were not related to any dimension of schizotypy. Smooth pursuit eye movement error was unrelated to sensory gating and latent inhibition, but was related to negative dimensions of schizotypy. Our findings suggest that the symptom clusters associated with two main endophenotypes are largely independent. To fully understand symptomology and outcomes of schizotypal traits, the different subtypes of schizotypy (and potentially, schizophrenia) ought to be considered separately rather than together.
https://eprints.bournemouth.ac.uk/35973/
Source: Scopus
Sensory gating is related to positive and disorganised schizotypy in contrast to smooth pursuit eye movements and latent inhibition.
Authors: Hills, P.J., Vasilev, M.R., Ford, P., Snell, L., Whitworth, E., Parsons, T., Morisson, R., Silveira, A. and Angele, B.
Journal: Neuropsychologia
Volume: 161
Pages: 107989
eISSN: 1873-3514
DOI: 10.1016/j.neuropsychologia.2021.107989
Abstract:Since the characteristics and symptoms of both schizophrenia and schizotypy are manifested heterogeneously, it is possible that different endophenotypes and neurophysiological measures (sensory gating and smooth pursuit eye movement errors) represent different clusters of symptoms. Participants (N = 205) underwent a standard conditioned-pairing paradigm to establish their sensory gating ratio, a smooth-pursuit eye-movement task, a latent inhibition task, and completed the Schizotypal Personality Questionnaire. A Multidimensional Scaling analysis revealed that sensory gating was related to positive and disorganised dimensions of schizotypy. Latent inhibition and prepulse inhibition were not related to any dimension of schizotypy. Smooth pursuit eye movement error was unrelated to sensory gating and latent inhibition, but was related to negative dimensions of schizotypy. Our findings suggest that the symptom clusters associated with two main endophenotypes are largely independent. To fully understand symptomology and outcomes of schizotypal traits, the different subtypes of schizotypy (and potentially, schizophrenia) ought to be considered separately rather than together.
https://eprints.bournemouth.ac.uk/35973/
Source: PubMed
Sensory gating is related to positive and disorganised schizotypy in contrast to smooth pursuit eye movements and latent inhibition
Authors: Hills, P.J., Vasilev, M.R., Ford, P., Snell, L., Whitworth, E., Parsons, T., Morisson, R., Silveira, A. and Angele, B.
Journal: NEUROPSYCHOLOGIA
Volume: 161
eISSN: 1873-3514
ISSN: 0028-3932
DOI: 10.1016/j.neuropsychologia.2021.107989
https://eprints.bournemouth.ac.uk/35973/
Source: Web of Science (Lite)
Sensory gating is related to positive and disorganised schizotypy in contrast to smooth pursuit eye movements and latent inhibition.
Authors: Hills, P.J., Vasilev, M.R., Ford, P., Snell, L., Whitworth, E., Parsons, T., Morisson, R., Silveira, A. and Angele, B.
Journal: Neuropsychologia
Volume: 161
Pages: 107989
eISSN: 1873-3514
ISSN: 0028-3932
DOI: 10.1016/j.neuropsychologia.2021.107989
Abstract:Since the characteristics and symptoms of both schizophrenia and schizotypy are manifested heterogeneously, it is possible that different endophenotypes and neurophysiological measures (sensory gating and smooth pursuit eye movement errors) represent different clusters of symptoms. Participants (N = 205) underwent a standard conditioned-pairing paradigm to establish their sensory gating ratio, a smooth-pursuit eye-movement task, a latent inhibition task, and completed the Schizotypal Personality Questionnaire. A Multidimensional Scaling analysis revealed that sensory gating was related to positive and disorganised dimensions of schizotypy. Latent inhibition and prepulse inhibition were not related to any dimension of schizotypy. Smooth pursuit eye movement error was unrelated to sensory gating and latent inhibition, but was related to negative dimensions of schizotypy. Our findings suggest that the symptom clusters associated with two main endophenotypes are largely independent. To fully understand symptomology and outcomes of schizotypal traits, the different subtypes of schizotypy (and potentially, schizophrenia) ought to be considered separately rather than together.
https://eprints.bournemouth.ac.uk/35973/
Source: Europe PubMed Central
Sensory gating is related to positive and disorganised schizotypy in contrast to smooth pursuit eye movements and latent inhibition.
Authors: Hills, P.J., Vasilev, M.R., Ford, P., Snell, L., Whitworth, E., Parsons, T., Morisson, R., Silveira, A. and Angele, B.
Journal: Neuropsychologia
Volume: 161
Issue: October
ISSN: 0028-3932
Abstract:Since the characteristics and symptoms of both schizophrenia and schizotypy are manifested heterogeneously, it is possible that different endophenotypes and neurophysiological measures (sensory gating and smooth pursuit eye movement errors) represent different clusters of symptoms. Participants (N = 205) underwent a standard conditioned-pairing paradigm to establish their sensory gating ratio, a smooth-pursuit eye-movement task, a latent inhibition task, and completed the Schizotypal Personality Questionnaire. A Multidimensional Scaling analysis revealed that sensory gating was related to positive and disorganised dimensions of schizotypy. Latent inhibition and prepulse inhibition were not related to any dimension of schizotypy. Smooth pursuit eye movement error was unrelated to sensory gating and latent inhibition, but was related to negative dimensions of schizotypy. Our findings suggest that the symptom clusters associated with two main endophenotypes are largely independent. To fully understand symptomology and outcomes of schizotypal traits, the different subtypes of schizotypy (and potentially, schizophrenia) ought to be considered separately rather than together.
https://eprints.bournemouth.ac.uk/35973/
Source: BURO EPrints