Both the cutaneous sensation and phosphene perception are modulated in a frequency-specific manner during transcranial alternating current stimulation

Authors: Turi, Z., Ambrus, G.G., Janacsek, K., Emmert, K., Hahn, L., Paulus, W. and Antal, A.

Journal: Restorative Neurology and Neuroscience

Volume: 31

Issue: 3

Pages: 275-285

eISSN: 1878-3627

ISSN: 0922-6028

DOI: 10.3233/RNN-120297

Abstract:

Purpose: Transcranial alternating current stimulation (tACS) is a non-invasive stimulation technique for shaping neuroplastic processes and possibly entraining ongoing neural oscillations in humans. Despite the growing number of studies using tACS, we know little about the procedural sensations caused by stimulation. In order to fill this gap, we explored the cutaneous sensation and phosphene perception during tACS. Methods: Twenty healthy participants took part in a randomized, single-blinded, sham-controlled study, where volunteers received short duration stimulation at 1.0mA intensity between 2 to 250 Hz using the standard left motor cortex - contralateral supraorbital montage.We recorded the perception onset latency and the strength of the sensations assessed by visual rating scale as dependent variables. Results: We found that tACS evoked both cutaneous sensation and phosphene perception in a frequency-dependent manner. Our results show that the most perceptible procedural sensations were induced in the beta and gamma frequency range, especially at 20 Hz, whereas minimal procedural sensations were indicated in the ripple range (140 and 250 Hz). Conclusions: We believe that our results provide a relevant insight into the procedural sensations caused by oscillatory currents, and will offer a basis for developing more sophisticated stimulation protocols and study designs for future investigations. © 2013 - IOS Press and the authors. All rights reserved.

Source: Scopus

Both the cutaneous sensation and phosphene perception are modulated in a frequency-specific manner during transcranial alternating current stimulation.

Authors: Turi, Z., Ambrus, G.G., Janacsek, K., Emmert, K., Hahn, L., Paulus, W. and Antal, A.

Journal: Restor Neurol Neurosci

Volume: 31

Issue: 3

Pages: 275-285

eISSN: 1878-3627

DOI: 10.3233/RNN-120297

Abstract:

PURPOSE: Transcranial alternating current stimulation (tACS) is a non-invasive stimulation technique for shaping neuroplastic processes and possibly entraining ongoing neural oscillations in humans. Despite the growing number of studies using tACS, we know little about the procedural sensations caused by stimulation. In order to fill this gap, we explored the cutaneous sensation and phosphene perception during tACS. METHODS: Twenty healthy participants took part in a randomized, single-blinded, sham-controlled study, where volunteers received short duration stimulation at 1.0 mA intensity between 2 to 250 Hz using the standard left motor cortex-contralateral supraorbital montage. We recorded the perception onset latency and the strength of the sensations assessed by visual rating scale as dependent variables. RESULTS: We found that tACS evoked both cutaneous sensation and phosphene perception in a frequency-dependent manner. Our results show that the most perceptible procedural sensations were induced in the beta and gamma frequency range, especially at 20 Hz, whereas minimal procedural sensations were indicated in the ripple range (140 and 250 Hz). CONCLUSIONS: We believe that our results provide a relevant insight into the procedural sensations caused by oscillatory currents, and will offer a basis for developing more sophisticated stimulation protocols and study designs for future investigations.

Source: PubMed

Both the cutaneous sensation and phosphene perception are modulated in a frequency-specific manner during transcranial alternating current stimulation

Authors: Turi, Z., Ambrus, G.G., Janacsek, K., Emmert, K., Hahn, L., Paulus, W. and Antal, A.

Journal: RESTORATIVE NEUROLOGY AND NEUROSCIENCE

Volume: 31

Issue: 3

Pages: 275-285

ISSN: 0922-6028

DOI: 10.3233/RNN-120297

Source: Web of Science (Lite)

Both the cutaneous sensation and phosphene perception are modulated in a frequency-specific manner during transcranial alternating current stimulation.

Authors: Turi, Z., Ambrus, G.G., Janacsek, K., Emmert, K., Hahn, L., Paulus, W. and Antal, A.

Journal: Restorative neurology and neuroscience

Volume: 31

Issue: 3

Pages: 275-285

eISSN: 1878-3627

ISSN: 0922-6028

DOI: 10.3233/rnn-120297

Abstract:

Purpose

Transcranial alternating current stimulation (tACS) is a non-invasive stimulation technique for shaping neuroplastic processes and possibly entraining ongoing neural oscillations in humans. Despite the growing number of studies using tACS, we know little about the procedural sensations caused by stimulation. In order to fill this gap, we explored the cutaneous sensation and phosphene perception during tACS.

Methods

Twenty healthy participants took part in a randomized, single-blinded, sham-controlled study, where volunteers received short duration stimulation at 1.0 mA intensity between 2 to 250 Hz using the standard left motor cortex-contralateral supraorbital montage. We recorded the perception onset latency and the strength of the sensations assessed by visual rating scale as dependent variables.

Results

We found that tACS evoked both cutaneous sensation and phosphene perception in a frequency-dependent manner. Our results show that the most perceptible procedural sensations were induced in the beta and gamma frequency range, especially at 20 Hz, whereas minimal procedural sensations were indicated in the ripple range (140 and 250 Hz).

Conclusions

We believe that our results provide a relevant insight into the procedural sensations caused by oscillatory currents, and will offer a basis for developing more sophisticated stimulation protocols and study designs for future investigations.

Source: Europe PubMed Central