Disagreement in FST estimators: A case study from sex chromosomes.
Authors: Gammerdinger, W.J., Toups, M.A. and Vicoso, B.
Journal: Mol Ecol Resour
Volume: 20
Issue: 6
Pages: 1517-1525
eISSN: 1755-0998
DOI: 10.1111/1755-0998.13210
Abstract:Sewall Wright developed FST for describing population differentiation and it has since been extended to many novel applications, including the detection of homomorphic sex chromosomes. However, there has been confusion regarding the expected estimate of FST for a fixed difference between the X- and Y-chromosome when comparing males and females. Here, we attempt to resolve this confusion by contrasting two common FST estimators and explain why they yield different estimates when applied to the case of sex chromosomes. We show that this difference is true for many allele frequencies, but the situation characterized by fixed differences between the X- and Y-chromosome is among the most extreme. To avoid additional confusion, we recommend that all authors using FST clearly state which estimator of FST their work uses.
Source: PubMed
Disagreement in<i>F</i><sub>ST</sub>estimators: A case study from sex chromosomes
Authors: Gammerdinger, W.J., Toups, M.A. and Vicoso, B.
Journal: MOLECULAR ECOLOGY RESOURCES
Volume: 20
Issue: 6
Pages: 1517-1525
eISSN: 1755-0998
ISSN: 1755-098X
DOI: 10.1111/1755-0998.13210
Source: Web of Science (Lite)
Disagreement in FST estimators: A case study from sex chromosomes
Authors: Gammerdinger, W.J., Toups, M.A. and Vicoso, B.
Journal: Molecular Ecology Resources
Issue: 20
Pages: 1517-1525
Publisher: Wiley-Blackwell
ISSN: 1471-8278
Source: Manual
Disagreement in F<sub>ST</sub> estimators: A case study from sex chromosomes.
Authors: Gammerdinger, W.J., Toups, M.A. and Vicoso, B.
Journal: Molecular ecology resources
Volume: 20
Issue: 6
Pages: 1517-1525
eISSN: 1755-0998
ISSN: 1755-0998
DOI: 10.1111/1755-0998.13210
Abstract:Sewall Wright developed FST for describing population differentiation and it has since been extended to many novel applications, including the detection of homomorphic sex chromosomes. However, there has been confusion regarding the expected estimate of FST for a fixed difference between the X- and Y-chromosome when comparing males and females. Here, we attempt to resolve this confusion by contrasting two common FST estimators and explain why they yield different estimates when applied to the case of sex chromosomes. We show that this difference is true for many allele frequencies, but the situation characterized by fixed differences between the X- and Y-chromosome is among the most extreme. To avoid additional confusion, we recommend that all authors using FST clearly state which estimator of FST their work uses.
Source: Europe PubMed Central