Health-related quality of life and functional outcome measures for pediatric multiple injury: A systematic review and narrative synthesis

Authors: Collins, K.C., Burdall, O., Kassam, J., Firth, G., Perry, D. and Ramachandran, M.

Journal: Journal of Trauma and Acute Care Surgery

Volume: 92

Issue: 5

Pages: E92-E106

eISSN: 2163-0763

ISSN: 2163-0755

DOI: 10.1097/TA.0000000000003457

Abstract:

BACKGROUND Pediatric multiple injury is a major cause of mortality and morbidity worldwide, with varied long-Term sequelae. To improve care, a better understanding of the outcome tools used following multiple injury is needed. OBJECTIVES This study aimed to (1) identify the outcome tools used to assess functional and health-related quality of life outcomes in pediatric multiple injury and to (2) describe the tool domains and validity. METHODS Eligible studies were those that included pediatric participants aged 0 to 17 years who experienced multiple injury or severe trauma based on Injury Severity Score/Abbreviated Injury Scale score and a functional outcome tool was used to assess outcomes (e.g., physical, psychological, quality of life). Excluded study designs were editorials, narrative, and systematic reviews. RESULTS Twenty-Two papers were included encompassing 16,905 participants and 34 different outcome tools. Ten tools were validated in children of which 4 were multiple injury specific; 18 were validated in adults of which 8 were trauma specific, and 6 were previously unvalidated. The tools were a mixture of patient reported (7 of 10 validated in children and 13 of 18 validated in adults) and clinician reported (3 of 10 validated in children and 2 of 13 validated in adults). Pediatric tool domains assessed were function, mobility, activities of daily living, pain, school, cognition, emotional domains, mental health, behavior, and high-risk behaviors. Using adult-validated tools to assess children may not capture the children's true function and health-related quality of life. CONCLUSION There was a lack of consistency in the outcome tools used following multiple injury in children. Adult-validated measures may not accurately capture pediatric outcomes after multiple injury. To fully understand the impact of pediatric multiple injury and make comparisons between studies, development of a core outcome set is required. LEVEL OF EVIDENCE Quantitative observational studies, level III.

Source: Scopus

Health-related quality of life and functional outcome measures for pediatric multiple injury: A systematic review and narrative synthesis.

Authors: Collins, K.C., Burdall, O., Kassam, J., Firth, G., Perry, D. and Ramachandran, M.

Journal: J Trauma Acute Care Surg

Volume: 92

Issue: 5

Pages: e92-e106

eISSN: 2163-0763

DOI: 10.1097/TA.0000000000003457

Abstract:

BACKGROUND: Pediatric multiple injury is a major cause of mortality and morbidity worldwide, with varied long-term sequelae. To improve care, a better understanding of the outcome tools used following multiple injury is needed. OBJECTIVES: This study aimed to (1) identify the outcome tools used to assess functional and health-related quality of life outcomes in pediatric multiple injury and to (2) describe the tool domains and validity. METHODS: Eligible studies were those that included pediatric participants aged 0 to 17 years who experienced multiple injury or severe trauma based on Injury Severity Score/Abbreviated Injury Scale score and a functional outcome tool was used to assess outcomes (e.g., physical, psychological, quality of life). Excluded study designs were editorials, narrative, and systematic reviews. RESULTS: Twenty-two papers were included encompassing 16,905 participants and 34 different outcome tools. Ten tools were validated in children of which 4 were multiple injury specific; 18 were validated in adults of which 8 were trauma specific, and 6 were previously unvalidated. The tools were a mixture of patient reported (7 of 10 validated in children and 13 of 18 validated in adults) and clinician reported (3 of 10 validated in children and 2 of 13 validated in adults). Pediatric tool domains assessed were function, mobility, activities of daily living, pain, school, cognition, emotional domains, mental health, behavior, and high-risk behaviors. Using adult-validated tools to assess children may not capture the children's true function and health-related quality of life. CONCLUSION: There was a lack of consistency in the outcome tools used following multiple injury in children. Adult-validated measures may not accurately capture pediatric outcomes after multiple injury. To fully understand the impact of pediatric multiple injury and make comparisons between studies, development of a core outcome set is required. LEVEL OF EVIDENCE: Quantitative observational studies, level III.

Source: PubMed

Health-related quality of life and functional outcome measures for pediatric multiple injury: A systematic review and narrative synthesis

Authors: Collins, K.C., Burdall, O., Kassam, J., Firth, G., Perry, D. and Ramachandran, M.

Journal: JOURNAL OF TRAUMA AND ACUTE CARE SURGERY

Volume: 92

Issue: 5

Pages: E92-E106

eISSN: 2163-0763

ISSN: 2163-0755

DOI: 10.1097/TA.0000000000003457

Source: Web of Science (Lite)

Health-related quality of life and functional outcome measures for pediatric multiple injury: A systematic review and narrative synthesis

Authors: Collins, K., Burdall, O., Kassam, J., Firth, G., Perry, D. and Ramachandran,, M.

Journal: Journal of Trauma and Acute Care Surgery

Publisher: Wolters Kluwer Health

ISSN: 2163-0755

DOI: 10.1097/TA.0000000000003457

Source: Manual

Health-related quality of life and functional outcome measures for pediatric multiple injury: A systematic review and narrative synthesis.

Authors: Collins, K.C., Burdall, O., Kassam, J., Firth, G., Perry, D. and Ramachandran, M.

Journal: The journal of trauma and acute care surgery

Volume: 92

Issue: 5

Pages: e92-e106

eISSN: 2163-0763

ISSN: 2163-0755

DOI: 10.1097/ta.0000000000003457

Abstract:

Background

Pediatric multiple injury is a major cause of mortality and morbidity worldwide, with varied long-term sequelae. To improve care, a better understanding of the outcome tools used following multiple injury is needed.

Objectives

This study aimed to (1) identify the outcome tools used to assess functional and health-related quality of life outcomes in pediatric multiple injury and to (2) describe the tool domains and validity.

Methods

Eligible studies were those that included pediatric participants aged 0 to 17 years who experienced multiple injury or severe trauma based on Injury Severity Score/Abbreviated Injury Scale score and a functional outcome tool was used to assess outcomes (e.g., physical, psychological, quality of life). Excluded study designs were editorials, narrative, and systematic reviews.

Results

Twenty-two papers were included encompassing 16,905 participants and 34 different outcome tools. Ten tools were validated in children of which 4 were multiple injury specific; 18 were validated in adults of which 8 were trauma specific, and 6 were previously unvalidated. The tools were a mixture of patient reported (7 of 10 validated in children and 13 of 18 validated in adults) and clinician reported (3 of 10 validated in children and 2 of 13 validated in adults). Pediatric tool domains assessed were function, mobility, activities of daily living, pain, school, cognition, emotional domains, mental health, behavior, and high-risk behaviors. Using adult-validated tools to assess children may not capture the children's true function and health-related quality of life.

Conclusion

There was a lack of consistency in the outcome tools used following multiple injury in children. Adult-validated measures may not accurately capture pediatric outcomes after multiple injury. To fully understand the impact of pediatric multiple injury and make comparisons between studies, development of a core outcome set is required.

Level of evidence

Quantitative observational studies, level III.

Source: Europe PubMed Central