Is oral fluid analysis as accurate as urinalysis in detecting drug use in a treatment setting?

Authors: Bennett, G.A., Davies, E. and Thomas, P.

Journal: Drug and Alcohol Dependence

Volume: 72

Issue: 3

Pages: 265-269

ISSN: 0376-8716

DOI: 10.1016/j.drugalcdep.2003.08.001

Abstract:

Background: Technology for testing oral fluid (OF) for the presence of drugs is available for treatment services and is more attractive than urinalysis: its validity is not well established. Aims: Compare the accuracy of methods of on-site testing of OF and urine. Design: Comparison of the sensitivity and specificity of on-site testing of samples of OF and urine collected on the same occasion, using subsequent blind laboratory analysis of the same urine samples as the standard. Setting: British addiction treatment service. Participants: 157 drug dependent persons, 89% with evidence of opiates, 73% male, and 85% aged between 20 and 35 years. Measurements: Assessment of presence of four drugs using SYVA ETS urinalysis and Cozart Rapiscan OF Drug Test systems. Laboratory urinalysis using microplate enzyme-immunoassay technique. Results: The sensitivity of OF tests and urinalysis were, respectively, for opiates 91 and 91%, methadone 91 and 94%, and benzodiazepines 6 and 72%. The specificity of OF tests and urinalysis were, respectively, for opiates 78 and 67%, methadone 90 and 95%, and benzodiazepines 95 and 96%. Amphetamine usage was rare. Conclusions: OF testing is as accurate as urinalysis in detecting the presence of opiates and methadone, and the absence of methadone and benzodiazepines. © 2003 Elsevier Ireland Ltd. All rights reserved.

Source: Scopus

Is oral fluid analysis as accurate as urinalysis in detecting drug use in a treatment setting?

Authors: Bennett, G.A., Davies, E. and Thomas, P.

Journal: Drug Alcohol Depend

Volume: 72

Issue: 3

Pages: 265-269

ISSN: 0376-8716

DOI: 10.1016/j.drugalcdep.2003.08.001

Abstract:

BACKGROUND: Technology for testing oral fluid (OF) for the presence of drugs is available for treatment services and is more attractive than urinalysis: its validity is not well established. AIMS: Compare the accuracy of methods of on-site testing of OF and urine. DESIGN: Comparison of the sensitivity and specificity of on-site testing of samples of OF and urine collected on the same occasion, using subsequent blind laboratory analysis of the same urine samples as the standard. SETTING: British addiction treatment service. PARTICIPANTS: 157 drug dependent persons, 89% with evidence of opiates, 73% male, and 85% aged between 20 and 35 years. MEASUREMENTS: Assessment of presence of four drugs using SYVA ETS urinalysis and Cozart Rapiscan OF Drug Test systems. Laboratory urinalysis using microplate enzyme-immunoassay technique. RESULTS: The sensitivity of OF tests and urinalysis were, respectively, for opiates 91 and 91%, methadone 91 and 94%, and benzodiazepines 6 and 72%. The specificity of OF tests and urinalysis were, respectively, for opiates 78 and 67%, methadone 90 and 95%, and benzodiazepines 95 and 96%. Amphetamine usage was rare. CONCLUSIONS: OF testing is as accurate as urinalysis in detecting the presence of opiates and methadone, and the absence of methadone and benzodiazepines.

Source: PubMed

Is oral fluid analysis as accurate as urinalysis in detecting drug use in a treatment setting?

Authors: Bennett, G.A., Davies, E. and Thomas, P.

Journal: DRUG AND ALCOHOL DEPENDENCE

Volume: 72

Issue: 3

Pages: 265-269

eISSN: 1879-0046

ISSN: 0376-8716

DOI: 10.1016/j.drugalcdep.2003.08.001

Source: Web of Science (Lite)

Is oral fluid analysis as accurate as urinanalysis in detecting drug use in a treatment setting?

Authors: Bennett, G., Davies, E. and Thomas, P.

Journal: Drug and Alcohol Dependence

Volume: 72

Pages: 265-269

ISSN: 0376-8716

DOI: 10.1016/j.drugalcdep.2003.08.001

Abstract:

Technology for testing oral fluid (OF) for the presence of drugs is available for treatment services and is more attractive than urinalysis: its validity is not well established. Aims: Compare the accuracy of methods of on-site testing of OF and urine. Design: Comparison of the sensitivity and specificity of on-site testing of samples of OF and urine collected on the same occasion, using subsequent blind laboratory analysis of the same urine samples as the standard. Setting: British addiction treatment service. Participants: 157 drug dependent persons, 89% with evidence of opiates, 73% male, and 85% aged between 20 and 35 years. Measurements: Assessment of presence of four drugs using SYVA ETS urinalysis and Cozart Rapiscan OF Drug Test systems. Laboratory urinalysis using microplate enzyme-immunoassay technique. Results: The sensitivity of OF tests and urinalysis were, respectively, for opiates 91 and 91%, methadone 91 and 94%, and benzodiazepines 6 and 72%. The specificity of OF tests and urinalysis were, respectively, for opiates 78 and 67%, methadone 90 and 95%, and benzodiazepines 95 and 96%. Amphetamine usage was rare. Conclusions: OF testing is as accurate as urinalysis in detecting the presence of opiates and methadone, and the absence of methadone and benzodiazepines.

Source: Manual

Is oral fluid analysis as accurate as urinalysis in detecting drug use in a treatment setting?

Authors: Bennett, G.A., Davies, E. and Thomas, P.

Journal: Drug and alcohol dependence

Volume: 72

Issue: 3

Pages: 265-269

eISSN: 1879-0046

ISSN: 0376-8716

DOI: 10.1016/j.drugalcdep.2003.08.001

Abstract:

Background

Technology for testing oral fluid (OF) for the presence of drugs is available for treatment services and is more attractive than urinalysis: its validity is not well established.

Aims

Compare the accuracy of methods of on-site testing of OF and urine.

Design

Comparison of the sensitivity and specificity of on-site testing of samples of OF and urine collected on the same occasion, using subsequent blind laboratory analysis of the same urine samples as the standard.

Setting

British addiction treatment service.

Participants

157 drug dependent persons, 89% with evidence of opiates, 73% male, and 85% aged between 20 and 35 years.

Measurements

Assessment of presence of four drugs using SYVA ETS urinalysis and Cozart Rapiscan OF Drug Test systems. Laboratory urinalysis using microplate enzyme-immunoassay technique.

Results

The sensitivity of OF tests and urinalysis were, respectively, for opiates 91 and 91%, methadone 91 and 94%, and benzodiazepines 6 and 72%. The specificity of OF tests and urinalysis were, respectively, for opiates 78 and 67%, methadone 90 and 95%, and benzodiazepines 95 and 96%. Amphetamine usage was rare.

Conclusions

OF testing is as accurate as urinalysis in detecting the presence of opiates and methadone, and the absence of methadone and benzodiazepines.

Source: Europe PubMed Central