Influence of hypoglycaemia, with or without caffeine ingestion, on visual sensation and performance.

Authors: Owen, G., Watson, J., McGown, A., Sharma, S., Deary, I., Kerr, D. and Barrett, G.

Journal: Clin Sci (Lond)

Volume: 100

Issue: 6

Pages: 619-626

ISSN: 0143-5221

Abstract:

Full-field visual evoked potentials and visual information processing were measured in 16 normal, healthy subjects during a hyperinsulinaemic clamp. A randomized cross-over design was used across three conditions: hypoglycaemia and caffeine; hypoglycaemia and placebo; and euglycaemia and caffeine. The latency of the P100 component of the pattern-reversal visual evoked potential increased significantly from rest to hypoglycaemia, but no effect of caffeine was found. Subjects were subsequently divided into two median groups based on the increase in P100 latency in the placebo condition (Group 1, +0.5 ms; Group 2, +5.6 ms). In the absence of caffeine, an inverse correlation between the increase in P100 latency from rest and a deterioration in visual movement detection was found for Group 2, but not for Group 1. Caffeine ingestion resulted in a further increase in P100 latency, from rest to hypoglycaemia, for subjects in Group 2. Hypoglycaemia in the absence of caffeine produces changes in visual sensation from rest to hypoglycaemia. In those subjects most sensitive to the effects of hypoglycaemia (Group 2), the increase in P100 latency was associated with poorer performance in tests of visual information processing. Caffeine ingestion produced further increases in P100 latency in these subjects.

Source: PubMed

Influence of hypoglycaemia, with or without caffeine ingestion, on visual sensation and performance

Authors: Owen, G., Watson, J., McGown, A., Sharma, S., Deary, I., Kerr, D. and Barrett, G.

Journal: CLINICAL SCIENCE

Volume: 100

Issue: 6

Pages: 619-626

eISSN: 1470-8736

ISSN: 0143-5221

DOI: 10.1042/CS20000332

Source: Web of Science (Lite)

Influence of hypoglycaemia, with or without caffeine ingestion, on visual sensation and performance

Authors: Owen, G., Watson, J.M., McGown, A., Sharma, S., Deary, I.A., Kerr, D. and Barrett, G.

Journal: Clinical Science

Volume: 100

Pages: 619-626

ISSN: 0143-5221

Abstract:

Full-field visual evoked potentials and visual information processing were measured in 16 normal, healthy subjects during a hyperinsulinaemic clamp. A randomized cross-over design was used across three conditions: hypoglycaemia and caffeine; hypoglycaemia and placebo; and euglycaemia and caffeine. The latency of the P100 component of the pattern-reversal visual evoked potential increased significantly from rest to hypoglycaemia, but no effect of caffeine was found. Subjects were subsequently divided into two median groups based on the increase in P100 latency in the placebo condition (Group 1, +0.5 ms; Group 2, +5.6 ms). In the absence of caffeine, an inverse correlation between the increase in P100 latency from rest and a deterioration in visual movement detection was found for Group 2, but not for Group 1. Caffeine ingestion resulted in a further increase in P100 latency, from rest to hypoglycaemia, for subjects in Group 2. Hypoglycaemia in the absence of caffeine produces changes in visual sensation from rest to hypoglycaemia. In those subjects most sensitive to the effects of hypoglycaemia (Group 2), the increase in P100 latency was associated with poorer performance in tests of visual information processing. Caffeine ingestion produced further increases in P100 latency in these subjects.

http://www.clinsci.org/cs/100/cs1000619.htm

Source: Manual

Preferred by: David Kerr

Influence of hypoglycaemia, with or without caffeine ingestion, on visual sensation and performance.

Authors: Owen, G., Watson, J., McGown, A., Sharma, S., Deary, I., Kerr, D. and Barrett, G.

Journal: Clinical science (London, England : 1979)

Volume: 100

Issue: 6

Pages: 619-626

eISSN: 1470-8736

ISSN: 0143-5221

DOI: 10.1042/cs1000619

Abstract:

Full-field visual evoked potentials and visual information processing were measured in 16 normal, healthy subjects during a hyperinsulinaemic clamp. A randomized cross-over design was used across three conditions: hypoglycaemia and caffeine; hypoglycaemia and placebo; and euglycaemia and caffeine. The latency of the P100 component of the pattern-reversal visual evoked potential increased significantly from rest to hypoglycaemia, but no effect of caffeine was found. Subjects were subsequently divided into two median groups based on the increase in P100 latency in the placebo condition (Group 1, +0.5 ms; Group 2, +5.6 ms). In the absence of caffeine, an inverse correlation between the increase in P100 latency from rest and a deterioration in visual movement detection was found for Group 2, but not for Group 1. Caffeine ingestion resulted in a further increase in P100 latency, from rest to hypoglycaemia, for subjects in Group 2. Hypoglycaemia in the absence of caffeine produces changes in visual sensation from rest to hypoglycaemia. In those subjects most sensitive to the effects of hypoglycaemia (Group 2), the increase in P100 latency was associated with poorer performance in tests of visual information processing. Caffeine ingestion produced further increases in P100 latency in these subjects.

Source: Europe PubMed Central