Randomized control trial investigating the influence of coffee on heart rate variability in patients with ST-segment elevation myocardial infarction
Authors: Richardson, T., Baker, J., Thomas, P.W., Meckes, C., Rozkovec, A. and Kerr, D.
Journal: QJM: An International Journal of Medicine
Volume: 102
Issue: 8
Pages: 555-561
eISSN: 1460-2393
ISSN: 1460-2725
DOI: 10.1093/qjmed/hcp072
Abstract:Background: Cardiac autonomic dysfunction post ST-segment elevation myocardial infarction (STEMI) has been linked to an excess risk of premature cardiovascular morbidity and mortality above those with normal autonomic function post-STEMI. Aim: The aim of this study was to evaluate the effect of acute ingestion of coffee on autonomic function and cardiovascular outcomes in patients with acute STEMI. Design: Randomized control trial. Methods: We randomized 103 patients with acute STEMI, admitted to our Coronary Care Unit, to receive regular coffee (caffeinated) or de-caffeinated coffee using a randomized controlled double-blinded design. Heart rate variability was assessed 5 days post-STEMI to assess the effect of caffeine on autonomic function. Results: In the group randomized to regular coffee, parasympathetic activity increased by up to 96% (P = 0.04) after 5 days. There was no detrimental effect of regular coffee on cardiac rhythm post-STEMI. Conclusion: Coffee ingestion is associated with an increase in parasympathetic autonomic function immediately post-STEMI. Coffee was found to be safe and not associated with any adverse cardiovascular outcomes in the short term. © The Author 2009. Published by Oxford University Press on behalf of the Association of Physicians. All rights reserved.
Source: Scopus
Randomized control trial investigating the influence of coffee on heart rate variability in patients with ST-segment elevation myocardial infarction.
Authors: Richardson, T., Baker, J., Thomas, P.W., Meckes, C., Rozkovec, A. and Kerr, D.
Journal: QJM
Volume: 102
Issue: 8
Pages: 555-561
eISSN: 1460-2393
DOI: 10.1093/qjmed/hcp072
Abstract:BACKGROUND: Cardiac autonomic dysfunction post ST-segment elevation myocardial infarction (STEMI) has been linked to an excess risk of premature cardiovascular morbidity and mortality above those with normal autonomic function post-STEMI. AIM: The aim of this study was to evaluate the effect of acute ingestion of coffee on autonomic function and cardiovascular outcomes in patients with acute STEMI. DESIGN: Randomized control trial. METHODS: We randomized 103 patients with acute STEMI, admitted to our Coronary Care Unit, to receive regular coffee (caffeinated) or de-caffeinated coffee using a randomized controlled double-blinded design. Heart rate variability was assessed 5 days post-STEMI to assess the effect of caffeine on autonomic function. RESULTS: In the group randomized to regular coffee, parasympathetic activity increased by up to 96% (P = 0.04) after 5 days. There was no detrimental effect of regular coffee on cardiac rhythm post-STEMI. CONCLUSION: Coffee ingestion is associated with an increase in parasympathetic autonomic function immediately post-STEMI. Coffee was found to be safe and not associated with any adverse cardiovascular outcomes in the short term.
Source: PubMed
Randomized control trial investigating the influence of coffee on heart rate variability in patients with ST-segment elevation myocardial infarction
Authors: Richardson, T., Baker, J., Thomas, P.W., Meckes, C., Rozkovec, A. and Kerr, D.
Journal: QJM-AN INTERNATIONAL JOURNAL OF MEDICINE
Volume: 102
Issue: 8
Pages: 555-561
eISSN: 1460-2393
ISSN: 1460-2725
DOI: 10.1093/qjmed/hcp072
Source: Web of Science (Lite)
Randomized control trial investigating the influence of coffee on heart rate variability in patients with ST-segment elevation myocardial infarction
Authors: Richardson, T., Baker, J., Thomas, P.W., Meckes, C., Rozkovec, A. and Kerr, D.
Journal: Quarterly Journal of Medicine
Volume: 102
Pages: 555-561
ISSN: 1460-2725
DOI: 10.1093/qjmed/hcp072
Abstract:Background: Cardiac autonomic dysfunction post ST-segment elevation myocardial infarction (STEMI) has been linked to an excess risk of premature cardiovascular morbidity and mortality above those with normal autonomic function post-STEMI. Aim: The aim of this study was to evaluate the effect of acute ingestion of coffee on autonomic function and cardiovascular outcomes in patients with acute STEMI. Design: Randomized control trial. Methods: We randomized 103 patients with acute STEMI, admitted to our Coronary Care Unit, to receive regular coffee (caffeinated) or de-caffeinated coffee using a randomized controlled double-blinded design. Heart rate variability was assessed 5 days post-STEMI to assess the effect of caffeine on autonomic function. Results: In the group randomized to regular coffee, parasympathetic activity increased by up to 96% (P = 0.04) after 5 days. There was no detrimental effect of regular coffee on cardiac rhythm post-STEMI. Conclusion: Coffee ingestion is associated with an increase in parasympathetic autonomic function immediately post-STEMI. Coffee was found to be safe and not associated with any adverse cardiovascular outcomes in the short term
Source: Manual
Preferred by: David Kerr
Randomized control trial investigating the influence of coffee on heart rate variability in patients with ST-segment elevation myocardial infarction.
Authors: Richardson, T., Baker, J., Thomas, P.W., Meckes, C., Rozkovec, A. and Kerr, D.
Journal: QJM : monthly journal of the Association of Physicians
Volume: 102
Issue: 8
Pages: 555-561
eISSN: 1460-2393
ISSN: 1460-2725
DOI: 10.1093/qjmed/hcp072
Abstract:Background
Cardiac autonomic dysfunction post ST-segment elevation myocardial infarction (STEMI) has been linked to an excess risk of premature cardiovascular morbidity and mortality above those with normal autonomic function post-STEMI.Aim
The aim of this study was to evaluate the effect of acute ingestion of coffee on autonomic function and cardiovascular outcomes in patients with acute STEMI.Design
Randomized control trial.Methods
We randomized 103 patients with acute STEMI, admitted to our Coronary Care Unit, to receive regular coffee (caffeinated) or de-caffeinated coffee using a randomized controlled double-blinded design. Heart rate variability was assessed 5 days post-STEMI to assess the effect of caffeine on autonomic function.Results
In the group randomized to regular coffee, parasympathetic activity increased by up to 96% (P = 0.04) after 5 days. There was no detrimental effect of regular coffee on cardiac rhythm post-STEMI.Conclusion
Coffee ingestion is associated with an increase in parasympathetic autonomic function immediately post-STEMI. Coffee was found to be safe and not associated with any adverse cardiovascular outcomes in the short term.Source: Europe PubMed Central