Lateral orbitofrontal cortex anticipates choices and integrates prior with current information
Authors: Nogueira, R., Abolafia, J.M., Drugowitsch, J., Balaguer-Ballester, E., Sanchez-Vives, M.V. and Moreno-Bote, R.
Journal: Nature Communications
Volume: 8
eISSN: 2041-1723
DOI: 10.1038/ncomms14823
Abstract:Adaptive behavior requires integrating prior with current information to anticipate upcoming events. Brain structures related to this computation should bring relevant signals from the recent past into the present. Here we report that rats can integrate the most recent prior information with sensory information, thereby improving behavior on a perceptual decision-making task with outcome-dependent past trial history. We find that anticipatory signals in the orbitofrontal cortex about upcoming choice increase over time and are even present before stimulus onset. These neuronal signals also represent the stimulus and relevant second-order combinations of past state variables. The encoding of choice, stimulus and second-order past state variables resides, up to movement onset, in overlapping populations. The neuronal representation of choice before stimulus onset and its build-up once the stimulus is presented suggest that orbitofrontal cortex plays a role in transforming immediate prior and stimulus information into choices using a compact state-space representation.
https://eprints.bournemouth.ac.uk/28369/
Source: Scopus
Preferred by: Emili Balaguer-Ballester
Lateral orbitofrontal cortex anticipates choices and integrates prior with current information.
Authors: Nogueira, R., Abolafia, J.M., Drugowitsch, J., Balaguer-Ballester, E., Sanchez-Vives, M.V. and Moreno-Bote, R.
Journal: Nat Commun
Volume: 8
Pages: 14823
eISSN: 2041-1723
DOI: 10.1038/ncomms14823
Abstract:Adaptive behavior requires integrating prior with current information to anticipate upcoming events. Brain structures related to this computation should bring relevant signals from the recent past into the present. Here we report that rats can integrate the most recent prior information with sensory information, thereby improving behavior on a perceptual decision-making task with outcome-dependent past trial history. We find that anticipatory signals in the orbitofrontal cortex about upcoming choice increase over time and are even present before stimulus onset. These neuronal signals also represent the stimulus and relevant second-order combinations of past state variables. The encoding of choice, stimulus and second-order past state variables resides, up to movement onset, in overlapping populations. The neuronal representation of choice before stimulus onset and its build-up once the stimulus is presented suggest that orbitofrontal cortex plays a role in transforming immediate prior and stimulus information into choices using a compact state-space representation.
https://eprints.bournemouth.ac.uk/28369/
Source: PubMed
Lateral orbitofrontal cortex anticipates choices and integrates prior with current information
Authors: Nogueira, R., Abolafia, J.M., Drugowitsch, J., Balaguer-Ballester, E., Sanchez-Vives, M.V. and Moreno-Bote, R.
Journal: NATURE COMMUNICATIONS
Volume: 8
ISSN: 2041-1723
DOI: 10.1038/ncomms14823
https://eprints.bournemouth.ac.uk/28369/
Source: Web of Science (Lite)
Lateral orbitofrontal cortex anticipates choices and integrates prior with current information
Authors: Nogueira, R., Abolafia, J., Drugowitsch, J., Balaguer-Ballester, E., Sanchez-Vives, M.V. and Moreno-Bote, R.
Journal: Nature Communications
Publisher: Nature Publishing Group: Nature Communications
ISSN: 2041-1723
https://eprints.bournemouth.ac.uk/28369/
Source: Manual
Lateral orbitofrontal cortex anticipates choices and integrates prior with current information.
Authors: Nogueira, R., Abolafia, J.M., Drugowitsch, J., Balaguer-Ballester, E., Sanchez-Vives, M.V. and Moreno-Bote, R.
Journal: Nature communications
Volume: 8
Pages: 14823
eISSN: 2041-1723
ISSN: 2041-1723
DOI: 10.1038/ncomms14823
Abstract:Adaptive behavior requires integrating prior with current information to anticipate upcoming events. Brain structures related to this computation should bring relevant signals from the recent past into the present. Here we report that rats can integrate the most recent prior information with sensory information, thereby improving behavior on a perceptual decision-making task with outcome-dependent past trial history. We find that anticipatory signals in the orbitofrontal cortex about upcoming choice increase over time and are even present before stimulus onset. These neuronal signals also represent the stimulus and relevant second-order combinations of past state variables. The encoding of choice, stimulus and second-order past state variables resides, up to movement onset, in overlapping populations. The neuronal representation of choice before stimulus onset and its build-up once the stimulus is presented suggest that orbitofrontal cortex plays a role in transforming immediate prior and stimulus information into choices using a compact state-space representation.
https://eprints.bournemouth.ac.uk/28369/
Source: Europe PubMed Central
Lateral orbitofrontal cortex anticipates choices and integrates prior with current information
Authors: Nogueira, R., Abolafia, J., Drugowitsch, J., Balaguer-Ballester, E., Sanchez-Vives, M.V. and Moreno-Bote, R.
Journal: Nature Communications
Volume: 8
Pages: 14823
ISSN: 2041-1723
Abstract:Adaptive behavior requires integrating prior with current information to anticipate upcoming events. Brain structures related to this computation should bring relevant signals from the recent past into the present. Here we report that rats can integrate the most recent prior information with sensory information, thereby improving behavior on a perceptual decision-making task with outcome-dependent past trial history. We find that anticipatory signals in the orbitofrontal cortex about upcoming choice increase over time and are even present before stimulus onset. These neuronal signals also represent the stimulus and relevant second-order combinations of past state variables. The encoding of choice, stimulus and second-order past state variables resides, up to movement onset, in overlapping populations. The neuronal representation of choice before stimulus onset and its build-up once the stimulus is presented suggest that orbitofrontal cortex plays a role in transforming immediate prior and stimulus information into choices using a compact state-space representation.
https://eprints.bournemouth.ac.uk/28369/
Source: BURO EPrints