Store operated calcium entry (SOCE) mediates insect nephrocyte clearance function

Authors: Hartley, P., Sivakumar, S. and Clarke, C.

Conference: British Society for Cell Biology Dynamic Cell IV

Dates: 14-19 March 2021

Abstract:

Insect nephrocytes are highly endocytic cells which remove proteins and xenotoxins from circulation (Figure 1). They express evolutionarily conserved ‘slit diaphragms’ at their surface; ultrastructures also expressed by mammalian kidney podocytes. Identifying nephrocyte signalling pathways is therefore important as they are relevant to clearance and renal function in many species, including humans. Establishing a method to investigate calcium signalling in nephrocytes was attempted in the current work.

http://eprints.bournemouth.ac.uk/36715/

Source: Manual

Store operated calcium entry (SOCE) mediates insect nephrocyte clearance function

Authors: Sivakumar, S., Clarke, C. and Hartley, P.S.

Conference: British Society for Cell Biology Dynamic Cell IV

Abstract:

Insect nephrocytes are highly endocytic cells which remove proteins and xenotoxins from circulation (Figure 1). They express evolutionarily conserved ‘slit diaphragms’ at their surface; ultrastructures also expressed by mammalian kidney podocytes. Identifying nephrocyte signalling pathways is therefore important as they are relevant to clearance and renal function in many species, including humans. Establishing a method to investigate calcium signalling in nephrocytes was attempted in the current work.

http://eprints.bournemouth.ac.uk/36715/

Source: BURO EPrints