Is there a role for n-3 long-chain polyunsaturated fatty acids in the regulation of mood and behaviour? A review of the evidence to date from epidemiological studies, clinical studies and intervention trials

Authors: Appleton, K.M., Rogers, P.J. and Ness, A.R.

Journal: Nutrition Research Reviews

Volume: 21

Issue: 1

Pages: 13-41

eISSN: 1475-2700

ISSN: 0954-4224

DOI: 10.1017/S0954422408998620

Abstract:

Selected biochemical evidence suggests a potential role for n-3 long-chain PUFA (n-3PUFA) in the regulation of mood and behaviour. The present paper reviews the relevant evidence, to date, from epidemiological studies, clinical studies and intervention trials. Most evidence is available investigating a role for n-3PUFA in depression, depressive illness and suicidal behaviour, but work is also available on anxiety and anxiety-related disorders, fatigue and fatigue-related disorders, aggression, hostility and anti-social behaviour, inattention, impulsivity and attention deficit hyperactivity disorder and schizophrenic disorders. For all these aspects of mood and behaviour, the evidence available is currently limited and highly inconsistent, both in terms of study methodology and study findings. There is a clear need for further work in this area. © The Authors 2008.

Source: Scopus

Preferred by: Katherine Appleton

Is there a role for n-3 long-chain polyunsaturated fatty acids in the regulation of mood and behaviour? A review of the evidence to date from epidemiological studies, clinical studies and intervention trials.

Authors: Appleton, K.M., Rogers, P.J. and Ness, A.R.

Journal: Nutr Res Rev

Volume: 21

Issue: 1

Pages: 13-41

eISSN: 1475-2700

DOI: 10.1017/S0954422408998620

Abstract:

Selected biochemical evidence suggests a potential role for n-3 long-chain PUFA (n-3PUFA) in the regulation of mood and behaviour. The present paper reviews the relevant evidence, to date, from epidemiological studies, clinical studies and intervention trials. Most evidence is available investigating a role for n-3PUFA in depression, depressive illness and suicidal behaviour, but work is also available on anxiety and anxiety-related disorders, fatigue and fatigue-related disorders, aggression, hostility and anti-social behaviour, inattention, impulsivity and attention deficit hyperactivity disorder and schizophrenic disorders. For all these aspects of mood and behaviour, the evidence available is currently limited and highly inconsistent, both in terms of study methodology and study findings. There is a clear need for further work in this area.

Source: PubMed

Is there a role for <i>n</i>-3 long-chain polyunsaturated fatty acids in the regulation of mood and behaviour? A review of the evidence to date from epidemiological studies, clinical studies and intervention trials

Authors: Appleton, K.M., Rogers, P.J. and Ness, A.R.

Journal: NUTRITION RESEARCH REVIEWS

Volume: 21

Issue: 1

Pages: 13-41

eISSN: 1475-2700

ISSN: 0954-4224

DOI: 10.1017/S0954422408998620

Source: Web of Science (Lite)

Is there a role for n-3 long-chain polyunsaturated fatty acids in the regulation of mood and behaviour? A review of the evidence to date from epidemiological studies, clinical studies and intervention trials.

Authors: Appleton, K.M., Rogers, P.J. and Ness, A.R.

Journal: Nutrition research reviews

Volume: 21

Issue: 1

Pages: 13-41

eISSN: 1475-2700

ISSN: 0954-4224

DOI: 10.1017/s0954422408998620

Abstract:

Selected biochemical evidence suggests a potential role for n-3 long-chain PUFA (n-3PUFA) in the regulation of mood and behaviour. The present paper reviews the relevant evidence, to date, from epidemiological studies, clinical studies and intervention trials. Most evidence is available investigating a role for n-3PUFA in depression, depressive illness and suicidal behaviour, but work is also available on anxiety and anxiety-related disorders, fatigue and fatigue-related disorders, aggression, hostility and anti-social behaviour, inattention, impulsivity and attention deficit hyperactivity disorder and schizophrenic disorders. For all these aspects of mood and behaviour, the evidence available is currently limited and highly inconsistent, both in terms of study methodology and study findings. There is a clear need for further work in this area.

Source: Europe PubMed Central