Detection of cannabinoids in hair after cosmetic application of hemp oil

Authors: Paul, R., Williams, R., Hodson, V. and Peake, C.

Journal: Scientific Reports

Volume: 9

Issue: 1

eISSN: 2045-2322

DOI: 10.1038/s41598-019-39609-0

Abstract:

The detection of cannabis constituents and metabolites in hair is an established procedure to provide evidence of exposure to cannabis. We present the first known evidence to suggest that applying hemp oil to hair, as cosmetic treatment, may result in the incorporation of Δ 9 -tetrahydrocannabinol (THC), cannabinol (CBN), cannabidiol (CBD) and in one instance, the metabolite 11-hydroxy-Δ 9 -tetrahydrocannabinol (THC-OH). 10 volunteers treated their head hair daily with commercially available hemp oil for a period of 6 weeks. Head hair samples were collected before and after the application period. Hair samples were washed with methanol and subjected to clean up via liquid/liquid and solid phase extraction procedures, and then GC-MS/MS for the analysis of THC, CBN, CBD, THC-OH and THC-COOH. Application of hemp oil to hair resulted in the incorporation of one or more cannabis constituents in 89% of volunteers, and 33% of the group tested positive for the three major constituents, THC, CBN and CBD. One volunteer showed low levels of the metabolite THC-OH. We suggest that cosmetic use of hemp oil should be recorded when sampling head hair for analysis, and that the interpretative value of cannabinoid hair measurements from people reporting application of hemp oil is treated with caution in both criminology and public health.

http://eprints.bournemouth.ac.uk/31887/

Source: Scopus

Detection of cannabinoids in hair after cosmetic application of hemp oil.

Authors: Paul, R., Williams, R., Hodson, V. and Peake, C.

Journal: Sci Rep

Volume: 9

Issue: 1

Pages: 2582

eISSN: 2045-2322

DOI: 10.1038/s41598-019-39609-0

Abstract:

The detection of cannabis constituents and metabolites in hair is an established procedure to provide evidence of exposure to cannabis. We present the first known evidence to suggest that applying hemp oil to hair, as cosmetic treatment, may result in the incorporation of Δ9-tetrahydrocannabinol (THC), cannabinol (CBN), cannabidiol (CBD) and in one instance, the metabolite 11-hydroxy-Δ9-tetrahydrocannabinol (THC-OH). 10 volunteers treated their head hair daily with commercially available hemp oil for a period of 6 weeks. Head hair samples were collected before and after the application period. Hair samples were washed with methanol and subjected to clean up via liquid/liquid and solid phase extraction procedures, and then GC-MS/MS for the analysis of THC, CBN, CBD, THC-OH and THC-COOH. Application of hemp oil to hair resulted in the incorporation of one or more cannabis constituents in 89% of volunteers, and 33% of the group tested positive for the three major constituents, THC, CBN and CBD. One volunteer showed low levels of the metabolite THC-OH. We suggest that cosmetic use of hemp oil should be recorded when sampling head hair for analysis, and that the interpretative value of cannabinoid hair measurements from people reporting application of hemp oil is treated with caution in both criminology and public health.

http://eprints.bournemouth.ac.uk/31887/

Source: PubMed

Detection of cannabinoids in hair after cosmetic application of hemp oil

Authors: Paul, R., Williams, R., Hodson, V. and Peake, C.

Journal: SCIENTIFIC REPORTS

Volume: 9

ISSN: 2045-2322

DOI: 10.1038/s41598-019-39609-0

http://eprints.bournemouth.ac.uk/31887/

Source: Web of Science (Lite)

Detection of cannabinoids in hair after cosmetic application of hemp oil.

Authors: Paul, R., Williams, R., Hodson, V. and Peake, C.

Journal: Scientific Reports

Publisher: Nature Publishing Group

ISSN: 2045-2322

DOI: 10.1038/s41598-019-39609-0

http://eprints.bournemouth.ac.uk/31887/

Source: Manual

Detection of cannabinoids in hair after cosmetic application of hemp oil.

Authors: Paul, R., Williams, R., Hodson, V. and Peake, C.

Journal: Scientific reports

Volume: 9

Issue: 1

Pages: 2582

eISSN: 2045-2322

ISSN: 2045-2322

DOI: 10.1038/s41598-019-39609-0

Abstract:

The detection of cannabis constituents and metabolites in hair is an established procedure to provide evidence of exposure to cannabis. We present the first known evidence to suggest that applying hemp oil to hair, as cosmetic treatment, may result in the incorporation of Δ9-tetrahydrocannabinol (THC), cannabinol (CBN), cannabidiol (CBD) and in one instance, the metabolite 11-hydroxy-Δ9-tetrahydrocannabinol (THC-OH). 10 volunteers treated their head hair daily with commercially available hemp oil for a period of 6 weeks. Head hair samples were collected before and after the application period. Hair samples were washed with methanol and subjected to clean up via liquid/liquid and solid phase extraction procedures, and then GC-MS/MS for the analysis of THC, CBN, CBD, THC-OH and THC-COOH. Application of hemp oil to hair resulted in the incorporation of one or more cannabis constituents in 89% of volunteers, and 33% of the group tested positive for the three major constituents, THC, CBN and CBD. One volunteer showed low levels of the metabolite THC-OH. We suggest that cosmetic use of hemp oil should be recorded when sampling head hair for analysis, and that the interpretative value of cannabinoid hair measurements from people reporting application of hemp oil is treated with caution in both criminology and public health.

http://eprints.bournemouth.ac.uk/31887/

Source: Europe PubMed Central

Detection of cannabinoids in hair after cosmetic application of hemp oil.

Authors: Paul, R., Williams, R., Hodson, V. and Peake, C.

Journal: Scientific Reports

Volume: 9

ISSN: 2045-2322

Abstract:

The detection of cannabis constituents and metabolites in hair is an established procedure to provide evidence of exposure to cannabis. We present the frst known evidence to suggest that applying hemp oil to hair, as cosmetic treatment, may result in the incorporation of Δ9-tetrahydrocannabinol (THC), cannabinol (CBN), cannabidiol (CBD) and in one instance, the metabolite 11-hydroxy-Δ9- tetrahydrocannabinol (THC-OH). 10 volunteers treated their head hair daily with commercially available hemp oil for a period of 6 weeks. Head hair samples were collected before and after the application period. Hair samples were washed with methanol and subjected to clean up via liquid/ liquid and solid phase extraction procedures, and then GC-MS/MS for the analysis of THC, CBN, CBD, THC-OH and THC-COOH. Application of hemp oil to hair resulted in the incorporation of one or more cannabis constituents in 89% of volunteers, and 33% of the group tested positive for the three major constituents, THC, CBN and CBD. One volunteer showed low levels of the metabolite THC-OH. We suggest that cosmetic use of hemp oil should be recorded when sampling head hair for analysis, and that the interpretative value of cannabinoid hair measurements from people reporting application of hemp oil is treated with caution in both criminology and public health.

http://eprints.bournemouth.ac.uk/31887/

Source: BURO EPrints