Self‐positivity or self‐negativity as a function of the medial prefrontal cortex

Authors: Yankouskaya, A. and Sui, J.

Journal: Brain Sciences

Volume: 11

Issue: 2

Pages: 1-17

eISSN: 2076-3425

DOI: 10.3390/brainsci11020264

Abstract:

Self and emotions are key motivational factors of a person strivings for health and well-being. Understanding neural mechanisms supporting the relationship between these factors bear far‐reaching implications for mental health disorders. Recent work indicates a substantial overlap between self‐relevant and emotion information processing and has proposed the medial prefrontal cortex (MPFC) as one shared neural signature. However, the precise cognitive and neural mechanisms represented by the MPFC in investigations of self‐ and emotion‐related processing are largely unknown. Here we examined whether the neural underpinnings of self‐related processing in the MPFC link to positive or negative emotions. We collected fMRI data to test the distinct and shared neural circuits of self‐ and emotion‐related processing while participants performed personal (self, friend, or stranger) and emotion (happy, sad, or neutral) associative matching tasks. By exploiting tight control over the factors that determine the effects of self‐relevance and emotions (positive: Happy vs. neutral; negative: Sad vs. neutral), our univariate analysis revealed that the ventral part of the MPFC (vmPFC), which has established involvement in self‐prioritisation effects, was not recruited in the negative emotion prioritisation effect. In contrast, there were no differences in brain activity between the effects of positive emotion‐ and self‐prioritisation. These results were replicated by both region of interest (ROI)‐based analysis in the vmPFC and the seed‐ to voxel functional connectivity analysis between the MPFC and the rest of the brain. The results suggest that the prioritisation effects for self and positive emotions are tightly linked together, and the MPFC plays a large role in discriminating between positive and negative emotions in relation to self‐relevance.

https://eprints.bournemouth.ac.uk/35057/

Source: Scopus

Self-Positivity or Self-Negativity as a Function of the Medial Prefrontal Cortex.

Authors: Yankouskaya, A. and Sui, J.

Journal: Brain Sci

Volume: 11

Issue: 2

ISSN: 2076-3425

DOI: 10.3390/brainsci11020264

Abstract:

Self and emotions are key motivational factors of a person strivings for health and well-being. Understanding neural mechanisms supporting the relationship between these factors bear far-reaching implications for mental health disorders. Recent work indicates a substantial overlap between self-relevant and emotion information processing and has proposed the medial prefrontal cortex (MPFC) as one shared neural signature. However, the precise cognitive and neural mechanisms represented by the MPFC in investigations of self- and emotion-related processing are largely unknown. Here we examined whether the neural underpinnings of self-related processing in the MPFC link to positive or negative emotions. We collected fMRI data to test the distinct and shared neural circuits of self- and emotion-related processing while participants performed personal (self, friend, or stranger) and emotion (happy, sad, or neutral) associative matching tasks. By exploiting tight control over the factors that determine the effects of self-relevance and emotions (positive: Happy vs. neutral; negative: Sad vs. neutral), our univariate analysis revealed that the ventral part of the MPFC (vmPFC), which has established involvement in self-prioritisation effects, was not recruited in the negative emotion prioritisation effect. In contrast, there were no differences in brain activity between the effects of positive emotion- and self-prioritisation. These results were replicated by both region of interest (ROI)-based analysis in the vmPFC and the seed- to voxel functional connectivity analysis between the MPFC and the rest of the brain. The results suggest that the prioritisation effects for self and positive emotions are tightly linked together, and the MPFC plays a large role in discriminating between positive and negative emotions in relation to self-relevance.

https://eprints.bournemouth.ac.uk/35057/

Source: PubMed

Self-Positivity or Self-Negativity as a Function of the Medial Prefrontal Cortex

Authors: Yankouskaya, A. and Sui, J.

Journal: BRAIN SCIENCES

Volume: 11

Issue: 2

eISSN: 2076-3425

DOI: 10.3390/brainsci11020264

https://eprints.bournemouth.ac.uk/35057/

Source: Web of Science (Lite)

Self-positivity or self-negativity as a function of the Medial Prefrontal Cortex

Authors: Yankouskaya, A. and Sue, J.

Editors: Molnar-Szakacs, I. and Uddin, L.Q.

Journal: Brain Sciences

Issue: Brain bases of conscious awareness and self-representation

Publisher: MDPI AG

ISSN: 2076-3425

Abstract:

Self and emotions are key motivational factors of a person’s strivings for health and well-being. Understanding neural mechanisms supporting the relationship between these factors bears far-reaching implications for mental health disorders. Recent work indicates a substantial overlap between processing of self-relevant and emotion information and proposed the MPFC as one of the neural signatures of the shared mechanisms. However, the precise cognitive and neural mechanisms represented by the MPFC are largely unknown. Here we addressed the question whether the neural underpinnings of self-related processing in the MPFC reflect positive or negative emotions. To test the distinct and shared neural circuits of self- and emotional-related processing, we collected fMRI data while participants performed personal and emotion associative matching tasks. By exploiting tight control over the factors that determine the effects of self-relevance and emotions, we contrasted these effects across the whole brain. We also assessed a seed-to voxel functional connectivity between the MPFC and the rest of the brain while accounting for the magnitude of self and emotions prioritization effects at the behavioural level. our univariate analysis revealed no differences in brain activation between the effects of self- and positive emotion-prioritization. Our results indicate that the ventral part of the MPFC which has established involvement in self-prioritization effects was not recruited in the negative emotion prioritization effect. In contrast, we found overlapping effects between self- and positive emotion prioritization. The results suggest that the prioritization effects for self and positive emotions are tightly linked together and the MPFC plays a large role in discriminating between positive and negative emotions in relation to self-relevance.

https://eprints.bournemouth.ac.uk/35057/

https://www.mdpi.com/journal/brainsci

Source: Manual

Self-Positivity or Self-Negativity as a Function of the Medial Prefrontal Cortex.

Authors: Yankouskaya, A. and Sui, J.

Journal: Brain sciences

Volume: 11

Issue: 2

Pages: 264

eISSN: 2076-3425

ISSN: 2076-3425

DOI: 10.3390/brainsci11020264

Abstract:

Self and emotions are key motivational factors of a person strivings for health and well-being. Understanding neural mechanisms supporting the relationship between these factors bear far-reaching implications for mental health disorders. Recent work indicates a substantial overlap between self-relevant and emotion information processing and has proposed the medial prefrontal cortex (MPFC) as one shared neural signature. However, the precise cognitive and neural mechanisms represented by the MPFC in investigations of self- and emotion-related processing are largely unknown. Here we examined whether the neural underpinnings of self-related processing in the MPFC link to positive or negative emotions. We collected fMRI data to test the distinct and shared neural circuits of self- and emotion-related processing while participants performed personal (self, friend, or stranger) and emotion (happy, sad, or neutral) associative matching tasks. By exploiting tight control over the factors that determine the effects of self-relevance and emotions (positive: Happy vs. neutral; negative: Sad vs. neutral), our univariate analysis revealed that the ventral part of the MPFC (vmPFC), which has established involvement in self-prioritisation effects, was not recruited in the negative emotion prioritisation effect. In contrast, there were no differences in brain activity between the effects of positive emotion- and self-prioritisation. These results were replicated by both region of interest (ROI)-based analysis in the vmPFC and the seed- to voxel functional connectivity analysis between the MPFC and the rest of the brain. The results suggest that the prioritisation effects for self and positive emotions are tightly linked together, and the MPFC plays a large role in discriminating between positive and negative emotions in relation to self-relevance.

https://eprints.bournemouth.ac.uk/35057/

Source: Europe PubMed Central

Self-positivity or self-negativity as a function of the Medial Prefrontal Cortex

Authors: Yankouskaya, A. and Sue, J.

Journal: Brain Sciences

Volume: 11

Issue: 2

ISSN: 2076-3425

Abstract:

Self and emotions are key motivational factors of a person’s strivings for health and well-being. Understanding neural mechanisms supporting the relationship between these factors bears far-reaching implications for mental health disorders. Recent work indicates a substantial overlap between processing of self-relevant and emotion information and proposed the MPFC as one of the neural signatures of the shared mechanisms. However, the precise cognitive and neural mechanisms represented by the MPFC are largely unknown. Here we addressed the question whether the neural underpinnings of self-related processing in the MPFC reflect positive or negative emotions. To test the distinct and shared neural circuits of self- and emotional-related processing, we collected fMRI data while participants performed personal and emotion associative matching tasks. By exploiting tight control over the factors that determine the effects of self-relevance and emotions, we contrasted these effects across the whole brain. We also assessed a seed-to voxel functional connectivity between the MPFC and the rest of the brain while accounting for the magnitude of self and emotions prioritization effects at the behavioural level. our univariate analysis revealed no differences in brain activation between the effects of self- and positive emotion-prioritization. Our results indicate that the ventral part of the MPFC which has established involvement in self-prioritization effects was not recruited in the negative emotion prioritization effect. In contrast, we found overlapping effects between self- and positive emotion prioritization. The results suggest that the prioritization effects for self and positive emotions are tightly linked together and the MPFC plays a large role in discriminating between positive and negative emotions in relation to self-relevance.

https://eprints.bournemouth.ac.uk/35057/

Source: BURO EPrints