Spatial navigation and visuospatial strategies in typical and atypical aging

Authors: Laczó, M., Wiener, J.M., Kalinova, J., Matuskova, V., Vyhnalek, M., Hort, J. and Laczó, J.

Journal: Brain Sciences

Volume: 11

Issue: 11

eISSN: 2076-3425

DOI: 10.3390/brainsci11111421

Abstract:

Age-related spatial navigation decline is more pronounced in patients with mild cognitive impairment (MCI) and Alzheimer’s disease (AD) dementia. We used a realistic-looking virtual navigation test suite to analyze different aspects of visuospatial processing in typical and atypical aging. A total of 219 older adults were recruited from the Czech Brain Aging Study cohort. Cognitively normal older adults (CN; n = 78), patients with amnestic MCI (n = 75), and those with mild AD dementia (n = 66) underwent three navigational tasks, cognitive assessment, and brain MRI. Route learning and wayfinding/perspective-taking tasks distinguished the groups as performance and learning declined and specific visuospatial strategies were less utilized with increasing cognitive impairment. Increased perspective shift and utilization of non-specific strategies were associated with worse task performance across the groups. Primacy and recency effects were observed across the groups in the route learning and the wayfinding/perspective-taking task, respectively. In addition, a primacy effect was present in the wayfinding/perspective-taking task in the CN older adults. More effective spatial navigation was associated with better memory and executive functions. The results demonstrate that a realistic and ecologically valid spatial navigation test suite can reveal different aspects of visuospatial processing in typical and atypical aging.

http://eprints.bournemouth.ac.uk/36226/

Source: Scopus

Spatial Navigation and Visuospatial Strategies in Typical and Atypical Aging.

Authors: Laczó, M., Wiener, J.M., Kalinova, J., Matuskova, V., Vyhnalek, M., Hort, J. and Laczó, J.

Journal: Brain Sci

Volume: 11

Issue: 11

ISSN: 2076-3425

DOI: 10.3390/brainsci11111421

Abstract:

Age-related spatial navigation decline is more pronounced in patients with mild cognitive impairment (MCI) and Alzheimer's disease (AD) dementia. We used a realistic-looking virtual navigation test suite to analyze different aspects of visuospatial processing in typical and atypical aging. A total of 219 older adults were recruited from the Czech Brain Aging Study cohort. Cognitively normal older adults (CN; n = 78), patients with amnestic MCI (n = 75), and those with mild AD dementia (n = 66) underwent three navigational tasks, cognitive assessment, and brain MRI. Route learning and wayfinding/perspective-taking tasks distinguished the groups as performance and learning declined and specific visuospatial strategies were less utilized with increasing cognitive impairment. Increased perspective shift and utilization of non-specific strategies were associated with worse task performance across the groups. Primacy and recency effects were observed across the groups in the route learning and the wayfinding/perspective-taking task, respectively. In addition, a primacy effect was present in the wayfinding/perspective-taking task in the CN older adults. More effective spatial navigation was associated with better memory and executive functions. The results demonstrate that a realistic and ecologically valid spatial navigation test suite can reveal different aspects of visuospatial processing in typical and atypical aging.

http://eprints.bournemouth.ac.uk/36226/

Source: PubMed

Spatial Navigation and Visuospatial Strategies in Typical and Atypical Aging

Authors: Laczo, M., Wiener, J.M., Kalinova, J., Matuskova, V., Vyhnalek, M., Hort, J. and Laczo, J.

Journal: BRAIN SCIENCES

Volume: 11

Issue: 11

eISSN: 2076-3425

DOI: 10.3390/brainsci11111421

http://eprints.bournemouth.ac.uk/36226/

Source: Web of Science (Lite)

Spatial Navigation and Visuospatial Strategies in Typical and Atypical Aging.

Authors: Laczó, M., Wiener, J.M., Kalinova, J., Matuskova, V., Vyhnalek, M., Hort, J. and Laczó, J.

Journal: Brain sciences

Volume: 11

Issue: 11

Pages: 1421

eISSN: 2076-3425

ISSN: 2076-3425

DOI: 10.3390/brainsci11111421

Abstract:

Age-related spatial navigation decline is more pronounced in patients with mild cognitive impairment (MCI) and Alzheimer's disease (AD) dementia. We used a realistic-looking virtual navigation test suite to analyze different aspects of visuospatial processing in typical and atypical aging. A total of 219 older adults were recruited from the Czech Brain Aging Study cohort. Cognitively normal older adults (CN; n = 78), patients with amnestic MCI (n = 75), and those with mild AD dementia (n = 66) underwent three navigational tasks, cognitive assessment, and brain MRI. Route learning and wayfinding/perspective-taking tasks distinguished the groups as performance and learning declined and specific visuospatial strategies were less utilized with increasing cognitive impairment. Increased perspective shift and utilization of non-specific strategies were associated with worse task performance across the groups. Primacy and recency effects were observed across the groups in the route learning and the wayfinding/perspective-taking task, respectively. In addition, a primacy effect was present in the wayfinding/perspective-taking task in the CN older adults. More effective spatial navigation was associated with better memory and executive functions. The results demonstrate that a realistic and ecologically valid spatial navigation test suite can reveal different aspects of visuospatial processing in typical and atypical aging.

http://eprints.bournemouth.ac.uk/36226/

Source: Europe PubMed Central

Spatial navigation and visuospatial strategies in typical and atypical aging

Authors: Laczó, M., Wiener, J.M., Kalinova, J., Matuskova, V., Vyhnalek, M., Hort, J. and Laczó, J.

Journal: Brain Sciences

Volume: 11

Issue: 11

ISSN: 2076-3425

Abstract:

Age-related spatial navigation decline is more pronounced in patients with mild cognitive impairment (MCI) and Alzheimer’s disease (AD) dementia. We used a realistic-looking virtual navigation test suite to analyze different aspects of visuospatial processing in typical and atypical aging. A total of 219 older adults were recruited from the Czech Brain Aging Study cohort. Cognitively normal older adults (CN; n = 78), patients with amnestic MCI (n = 75), and those with mild AD dementia (n = 66) underwent three navigational tasks, cognitive assessment, and brain MRI. Route learning and wayfinding/perspective-taking tasks distinguished the groups as performance and learning declined and specific visuospatial strategies were less utilized with increasing cognitive impairment. Increased perspective shift and utilization of non-specific strategies were associated with worse task performance across the groups. Primacy and recency effects were observed across the groups in the route learning and the wayfinding/perspective-taking task, respectively. In addition, a primacy effect was present in the wayfinding/perspective-taking task in the CN older adults. More effective spatial navigation was associated with better memory and executive functions. The results demonstrate that a realistic and ecologically valid spatial navigation test suite can reveal different aspects of visuospatial processing in typical and atypical aging.

http://eprints.bournemouth.ac.uk/36226/

Source: BURO EPrints