The impact of endoscopic ultrasound on the management and outcome of patients with oesophageal cancer: an update of a systematic review
Authors: Foley, K.G., Franklin, J., Jones, C.M., Coles, B., Roberts, S.A., Underwood, T.J. and Crosby, T.
Journal: Clinical Radiology
Volume: 77
Issue: 5
Pages: e346-e355
eISSN: 1365-229X
ISSN: 0009-9260
DOI: 10.1016/j.crad.2022.02.001
Abstract:AIM: To provide an updated systematic review concerning the impact of endoscopic ultrasound (EUS) in the modern era of oesophageal cancer staging. MATERIALS AND METHODS: To update the previous systematic review, databases including MEDLINE and EMBASE were searched and studies published from 2005 onwards were selected. Studies reporting primary data in patients with oesophageal or gastro-oesophageal junction cancer who underwent radiological staging and treatment, regardless of intent, were included. The primary outcome was the reported change in management after EUS. Secondary outcomes were recurrence rate and overall survival. Two reviewers extracted data from included articles. This study was registered with PROSPERO (CRD42021231852). RESULTS: Eighteen studies with 11,836 patients were included comprising 2,805 patients (23.7%) who underwent EUS compared to 9,031 (76.3%) without EUS examination. Reported change of management varied widely from 0% to 56%. When used, EUS fine-needle aspiration precluded curative treatment in 37.5%–71.4%. Overall survival improvements ranged between 121 and 639 days following EUS intervention compared to patients without EUS. Smaller effect sizes were observed in a randomised controlled trial, compared to larger differences reported in observational studies. CONCLUSION: Current evidence for the effectiveness of EUS in oesophageal cancer pathways is conflicting and of limited quality. In particular, the extent to which EUS adds value to contemporary cross-sectional imaging techniques is unclear and requires formal re-evaluation.
Source: Scopus
The impact of endoscopic ultrasound on the management and outcome of patients with oesophageal cancer: an update of a systematic review.
Authors: Foley, K.G., Franklin, J., Jones, C.M., Coles, B., Roberts, S.A., Underwood, T.J. and Crosby, T.
Journal: Clin Radiol
Volume: 77
Issue: 5
Pages: e346-e355
eISSN: 1365-229X
DOI: 10.1016/j.crad.2022.02.001
Abstract:AIM: To provide an updated systematic review concerning the impact of endoscopic ultrasound (EUS) in the modern era of oesophageal cancer staging. MATERIALS AND METHODS: To update the previous systematic review, databases including MEDLINE and EMBASE were searched and studies published from 2005 onwards were selected. Studies reporting primary data in patients with oesophageal or gastro-oesophageal junction cancer who underwent radiological staging and treatment, regardless of intent, were included. The primary outcome was the reported change in management after EUS. Secondary outcomes were recurrence rate and overall survival. Two reviewers extracted data from included articles. This study was registered with PROSPERO (CRD42021231852). RESULTS: Eighteen studies with 11,836 patients were included comprising 2,805 patients (23.7%) who underwent EUS compared to 9,031 (76.3%) without EUS examination. Reported change of management varied widely from 0% to 56%. When used, EUS fine-needle aspiration precluded curative treatment in 37.5%-71.4%. Overall survival improvements ranged between 121 and 639 days following EUS intervention compared to patients without EUS. Smaller effect sizes were observed in a randomised controlled trial, compared to larger differences reported in observational studies. CONCLUSION: Current evidence for the effectiveness of EUS in oesophageal cancer pathways is conflicting and of limited quality. In particular, the extent to which EUS adds value to contemporary cross-sectional imaging techniques is unclear and requires formal re-evaluation.
Source: PubMed
The impact of endoscopic ultrasound on the management and outcome of patients with oesophageal cancer: an update of a systematic review
Authors: Foley, K.G., Franklin, J., Jones, C.M., Coles, B., Roberts, S.A., Underwood, T.J. and Crosby, T.
Journal: CLINICAL RADIOLOGY
Volume: 77
Issue: 5
Pages: E346-E355
eISSN: 1365-229X
ISSN: 0009-9260
DOI: 10.1016/j.crad.2022.02.001
Source: Web of Science (Lite)
The impact of endoscopic ultrasound on the management and outcome of patients with oesophageal cancer: an update of a systematic review.
Authors: Foley, K.G., Franklin, J., Jones, C.M., Coles, B., Roberts, S.A., Underwood, T.J. and Crosby, T.
Journal: Clinical radiology
Volume: 77
Issue: 5
Pages: e346-e355
eISSN: 1365-229X
ISSN: 0009-9260
DOI: 10.1016/j.crad.2022.02.001
Abstract:Aim
To provide an updated systematic review concerning the impact of endoscopic ultrasound (EUS) in the modern era of oesophageal cancer staging.Materials and methods
To update the previous systematic review, databases including MEDLINE and EMBASE were searched and studies published from 2005 onwards were selected. Studies reporting primary data in patients with oesophageal or gastro-oesophageal junction cancer who underwent radiological staging and treatment, regardless of intent, were included. The primary outcome was the reported change in management after EUS. Secondary outcomes were recurrence rate and overall survival. Two reviewers extracted data from included articles. This study was registered with PROSPERO (CRD42021231852).Results
Eighteen studies with 11,836 patients were included comprising 2,805 patients (23.7%) who underwent EUS compared to 9,031 (76.3%) without EUS examination. Reported change of management varied widely from 0% to 56%. When used, EUS fine-needle aspiration precluded curative treatment in 37.5%-71.4%. Overall survival improvements ranged between 121 and 639 days following EUS intervention compared to patients without EUS. Smaller effect sizes were observed in a randomised controlled trial, compared to larger differences reported in observational studies.Conclusion
Current evidence for the effectiveness of EUS in oesophageal cancer pathways is conflicting and of limited quality. In particular, the extent to which EUS adds value to contemporary cross-sectional imaging techniques is unclear and requires formal re-evaluation.Source: Europe PubMed Central