James Franklin

Dr James Franklin

  • 01202 961748
  • jfranklin at bournemouth dot ac dot uk
  • Head Of Institute For Medical Imaging and Visualisation And Associate Professor
  • RLH R107
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Biography

Dr Jamie Franklin is a Consultant Gastrointestinal and Hepatopancreaticobiliary Radiologist at the Royal Bournemouth Hospital, and Head of the Institute of Medical Imaging and Visualisation. He studied Medicine at Cambridge University and Imperial College London before undertaking an NIHR Academic Clinical Fellowship in Oxford, where he completed specialist training in Radiology. Subsequently, he undertook DPhil at the University of Oxford, as part of the CRUK/EPSRC-funded Oxford Cancer Imaging Centre, studying oligometastatic colorectal cancer. He currently serves on the British Society of Gastrointestinal and Abdominal Radiology (BSGAR) Committee, and is the radiology representative on the National Oesophagogastric Cancer Audit (NOGCA). He is a regular invited speaker at the Royal College of Radiologists, British Institute of Radiology and BSGAR Annual Meetings.

Research

Jamie's research has predominantly focused on using MRI and other advanced imaging techniques to stage cancer and assess tumour biology. He has collaborated across multiple clinical and academic disciplines, from genetics and histopathology to engineering and surgery, and remains passionate about cross-disciplinary working. He is currently local PI on the Sunflower and MOTILITY multicentre imaging studies.

Favourites

  • Jones, R.P., Brudvik, K.W., Franklin, J. and Poston, G.J., 2017. Precision surgery for colorectal liver metastases: Opportunities and challenges of omics-based decision making. European Journal of Surgical Oncology, 43 (5), 875-883.
  • Franklin, J., Sharma, R.A., Harris, A.L. and Gleeson, F.V., 2016. Imaging oligometastatic cancer before local treatment. Lancet Oncology (Science Direct).
  • Franklin, J., Gebski, V., Poston, G.J. and Sharma, R.A., 2015. Clinical trials of interventional oncology—moving from efficacy to outcomes. Nature Reviews Clinical Oncology.

Journal Articles

  • Franklin, J.M. et al., 2020. Tumour subregion analysis of colorectal liver metastases using semi-automated clustering based on DCE-MRI: Comparison with histological subregions and impact on pharmacokinetic parameter analysis. European Journal of Radiology, 126.
  • Papież, B.W., Franklin, J.M., Heinrich, M.P., Gleeson, F.V., Brady, M. and Schnabel, J.A., 2018. GIFTed Demons: deformable image registration with local structure-preserving regularization using supervoxels for liver applications. J Med Imag, 5 (2), 1-14.
  • Jones, R.P., Brudvik, K.W., Franklin, J. and Poston, G.J., 2017. Precision surgery for colorectal liver metastases: Opportunities and challenges of omics-based decision making. European Journal of Surgical Oncology, 43 (5), 875-883.
  • Findlay, J.M., Bradley, K.M., Wang, L.M., Franklin, J., Teoh, E.J. and Gleeson, F.V., 2017. Metabolic nodal response as a prognostic marker after neoadjuvant therapy for oesophageal cancer. British Journal of Surgery: BJS, 104 (4), 408-417.
  • Franklin, J., Irving, B., Papież, B.W., Kallehauge, J., Anderson, E.M., Wang, L., Goldin, R., Brady, M. and Gleeson, F.V., 2017. Tumour subregion analysis of colorectal liver metastases using DSE-MRI: comparison with histological subregions and impact on PK analysis. Insights into Imaging, 8 (2017) ((Suppl1)), S1-S583.
  • Findlay, J.M., Bradley, K.M., Wang, L.M., Franklin, J., Teoh, E.J. and Gleeson, F.V., 2017. Predicting Pathologic Response of Esophageal Cancer to Neoadjuvant Chemotherapy: The Implications of Metabolic Nodal Response for Personalized Therapy. European Journal of Nuclear Medicine, 58 (2), 266-275.
  • Franklin, J., Sharma, R.A., Harris, A.L. and Gleeson, F.V., 2016. Imaging oligometastatic cancer before local treatment. Lancet Oncology (Science Direct).
  • Irving, B., Franklin, J., Papież, B.W., Anderson, E.M., Sharma, R.A. and Gleeson, F.V., 2016. Pieces-of-parts for supervoxel segmentation with global context: Application to DCE-MRI tumour delineation. Medical Image Analysis, 69-83.
  • Hill, E.J., Roberts, C., Franklin, J., Enescu, M., West, N. and MacGregor, T.P., 2016. Clinical Trial of Oral Nelfinavir before and during Radiation Therapy for Advanced Rectal Cancer. Clinical cancer research, 22 (8), 1922-1931.
  • Papież, B.W., Franklin, J., Heinrich, M.P., Gleeson, F.V. and Schnabel, J.A., 2015. Liver Motion Estimation via Locally Adaptive Over-Segmentation Regularization. Lecture Notes in Computer Science, 9351, 427-434.
  • Franklin, J., Papież, B.W., Heinrich, M.P., Gleeson, F.V. and Schnabel, J.A., 2015. Liver Motion Estimation via Locally Adaptive Over-Segmentation Regularization. MICCAI, 427-434.
  • Parvizi, N., Franklin, J., McGowan, D., Teoh, E.J., Bradley, K.M. and Gleeson, F.V., 2015. Does a novel penalized likelihood reconstruction of 18F-FDG PET-CT improve signal-to-background in colorectal liver metastases? European Journal of Radiology, 84 (10), 1873-1878.
  • Franklin, J., Gebski, V., Poston, G.J. and Sharma, R.A., 2015. Clinical trials of interventional oncology—moving from efficacy to outcomes. Nature Reviews Clinical Oncology.
  • Stedmand, J.M., Franklin, J., Nicholl, H., Anderson, E.M. and Moore, N.R., 2014. Splenic parenchymal heterogeneity at dual-bolus single-acquisition CT in polytrauma patients-6-months experience from Oxford, UK. Emergency Radiology, 21 (3), 257-260.
  • Irving, B., Cifor, A., Papież, B.W., Franklin, J., Anderson, E.M., Brady, M. and Schnabel, J.A., 2014. Automated Colorectal Tumour Segmentation in DCE-MRI Using Supervoxel Neighbourhood Contrast Characteristics. MICCAI, 609-619.
  • Irving, B., Tanner, L., Enescu, M., Bhushan, M., Hill, E.J., Franklin, J., Anderson, E.M., Sharma, R.A., Schnabel, J.A. and Brady, M., 2013. Personalised Estimation of the Arterial Input Function for Improved Pharmacokinetic Modelling of Colorectal Cancer Using dceMRI. Abdominal Imaging: Computation and Clinical Applications.
  • Enescu, M., Bhushan, M., Hill, E.J., Franklin, J., Anderson, E.M., Sharma, R.A. and Schnabel, J.A., 2013. pCT derived arterial input function for improved pharmacokinetic analysis of longitudinal dceMRI for colorectal cancer. Proceedings of SPIE Medical Imaging 2013.
  • Bhushan, M., Schnabel, J.A., Chappell, M., Gleeson, F.V., Anderson, E.M., Franklin, J., Brady, M. and Jenkinson, M., 2013. The impact of heterogeneity and uncertainty on prediction of response to therapy using dynamic MRI data. MICCAI 2013, 16 (1).
  • Franklin, J., Anderson, E.M. and Gleeson, F.V., 2012. MRI appearances of the Complete Pathological Response of Locally Advanced Rectal Cancer to Neoadjuvant Chemoradiotherapy. Clinical Radiology, 67 (6), 546-552.
  • Franklin, J., Rahman, N. and Gleeson, F.V., 2011. Clinicians’ Response to a Report of an Incidental Pulmonary Emboli on MDCT. Postgraduate medical journal, 87 (1033), 746-749.
  • Franklin, J., Purcell-Jones, J., Helm, E., Benamore, R. and Gleeson, F.V., 2011. Appearances of Empyema on Computed Tomography – Analysis of the MIST 2 Cohort. Thorax, 66 (4).
  • Franklin, J., Douglas, M., Clarke, A., Nartey, G., Tookey, P., Cortina-Borja, M., Smith, J. and Taylor, G.P., 2008. Interpretation of Serum a-fetoprotein, Human Chorionic Gonadotrophin and the Risk of Down's Syndrome in Pregnant Women Infected with HIV. Proceedings of 15th Conference on Retrovirology and Opportunistic Infections.
  • Csipke, E., Touquet, R., Patel, T., Franklin, J., Brown, A., Holloway, P., Batrick, N. and Crawford, M.J., 2007. The Use of blood Alcohol Concentration in Resuscitation Room Patients. Emergency Medicine Journal : EMJ, 24 (8), 535-538.
  • Foran, A., Fitzpatrick, J., Allsop, J., Schmitz, S. and Franklin, J., 2007. 3.0 Tesla Cardiac Magnetic Resonance Imaging in Preterm Infants. Pediatrics, 120 (1), 78-83.

Books

  • The Oxford Handbook of Key Clinical Evidence 2e. Oxford University Press.

Invited Lectures

  • Acute Abdominal Imaging, BSGAR Workshop, 08 Feb 2019 more
  • Pancreatic Intervention, BSGAR Registrar Study Day, 05 Nov 2018 more
  • Incidental pancreatic cysts - what to do next, BIR Annual Congress, 02 Nov 2018 more
  • Small pancreatic cysts, Royal College of Radiologists ASM, 10 Sep 2018 more
  • BSGAR Gallbladder Workshop, RCR ASM, 13 Sep 2017 more
  • BSGAR Pancreas Workshop, RCR ASM, 13 Sep 2017 more
  • What we do in Academic Radiology, Annual BIR Trainee Meeting, 19 Nov 2015 more
  • Imaging Biomarkers in Colorectal Cancer, 2nd Colorectal Cancer Network meeting, 19 Mar 2015 more
  • What we do in Academic Radiology, Annual BIR Trainee Meeting, 13 Nov 2014 more

Grants

  • Genetic analyses to support DPhil: Imaging Biomarkers in Oligometastatic Colorectal Cancer (Cancer Research UK Development Fund, 01 Jan 2015). Awarded
  • Dynamic CT for Pulmonary Nodules (SPUTNIK Trial) (NIHR-HTA Grant, 01 Jan 2009). Awarded
  • The assessment of colorectal liver metastases by perfusion CT, dynamic contrast enhanced MRI and FDG-PET: their relationships, prognostic value and correlation with tumour biology (Oxford Health Sciences Research Committee, 01 Jan 2009). Awarded
  • Tumour vascularity and metabolism in oesophageal cancer by initial dceCT and FDG-PET: their relationship and prognostic value. (Royal College of Radiologists Small Project Grant, 01 Jan 2008). Awarded
  • Towards establishing a Professional, Law and Ethics course at Imperial College, London (Institute of Medical Ethics Education Grant, 01 Jan 2007). Awarded

Qualifications

  • DPhil in Radiobiology (University of Oxford, 2019)
  • Postgraduate Diploma in Evidence Based Healthcare (University of Oxford, 2012)
  • MBBS in Clinical Medicine (Imperial College, University of London, 2007)
  • MA in Pre-clinical Medicine and Experimental Psychology (University of Cambridge, 2004)

Memberships

  • ESGAR, Member (2019-),
  • BSGAR, Member (2012-),
  • Royal College of Radiologists, Fellow (2012-),
The data on this page was last updated at 04:17 on August 4, 2020.