Persistent task-specific impairment of holistic face processing in acquired prosopagnosia

Authors: Leong, B.Q.Z., Hussain Ismail, A.M. and Estudillo, A.J.

Journal: Scientific Reports

Volume: 15

Issue: 1

eISSN: 2045-2322

DOI: 10.1038/s41598-025-28666-3

Abstract:

Face recognition deficits observed in Acquired Prosopagnosia are typically associated with impaired holistic processing. Nonetheless, whether this deficit is task-dependent, face-specific, and persistent over time has been under investigated. The present study examined the role of holistic processing in a case of acquired prosopagnosia (Patient DS). Patient DS, along with several neurotypical participants, completed the three standard measures of holistic face processing: the face inversion, part-whole, and composite face tasks, as well as a measure of non-face global processing: the Navon task. Our single-case analyses indicated that, compared to neurotypical participants, DS showed (1) impaired inversion effects, but (2) comparable part-whole and composite face effects, as well as (3) comparable global precedence effect in the Navon task. Interestingly, the same pattern of preserved and impaired holistic processing was observed in a second evaluation of DS four years later. While these findings suggest that holistic processing deficits in Acquired Prosopagnosia may be task-specific and persist over time—pointing toward the potential chronicity of the impairment—they should be interpreted with caution, given the floor effects and the single-case design.

Source: Scopus

Persistent task-specific impairment of holistic face processing in acquired prosopagnosia.

Authors: Leong, B.Q.Z., Hussain Ismail, A.M. and Estudillo, A.J.

Journal: Sci Rep

Volume: 15

Issue: 1

Pages: 43115

eISSN: 2045-2322

DOI: 10.1038/s41598-025-28666-3

Abstract:

Face recognition deficits observed in Acquired Prosopagnosia are typically associated with impaired holistic processing. Nonetheless, whether this deficit is task-dependent, face-specific, and persistent over time has been under investigated. The present study examined the role of holistic processing in a case of acquired prosopagnosia (Patient DS). Patient DS, along with several neurotypical participants, completed the three standard measures of holistic face processing: the face inversion, part-whole, and composite face tasks, as well as a measure of non-face global processing: the Navon task. Our single-case analyses indicated that, compared to neurotypical participants, DS showed (1) impaired inversion effects, but (2) comparable part-whole and composite face effects, as well as (3) comparable global precedence effect in the Navon task. Interestingly, the same pattern of preserved and impaired holistic processing was observed in a second evaluation of DS four years later. While these findings suggest that holistic processing deficits in Acquired Prosopagnosia may be task-specific and persist over time-pointing toward the potential chronicity of the impairment-they should be interpreted with caution, given the floor effects and the single-case design.

Source: PubMed

Persistent task-specific impairment of holistic face processing in acquired prosopagnosia

Authors: Leong, B.Q.Z., Hussain Ismail, A.M. and Estudillo, A.J.

Journal: SCIENTIFIC REPORTS

Volume: 15

Issue: 1

ISSN: 2045-2322

DOI: 10.1038/s41598-025-28666-3

Source: Web of Science (Lite)

Persistent task-specific impairment of holistic face processing in acquired prosopagnosia

Authors: Leong Qi Zheng, B., Hussain Ismail, A.M. and Estudillo, A.

Journal: Scientific Reports

Volume: 15

Publisher: Nature Portfolio

eISSN: 2045-2322

ISSN: 2045-2322

DOI: 10.1038/s41598-025-28666-3

Abstract:

Face recognition deficits observed in Acquired Prosopagnosia are typically associated with impaired holistic processing. Nonetheless, whether this deficit is task-dependent, face-specific, and persistent over time has been under investigated. The present study examined the role of holistic processing in a case of acquired prosopagnosia (Patient DS). Patient DS, along with several neurotypical participants, completed the three standard measures of holistic face processing: the face inversion, part-whole, and composite face tasks, as well as a measure of non-face global processing: the Navon task. Our single-case analyses indicated that, compared to neurotypical participants, DS showed (1) impaired inversion effects, but (2) comparable part-whole and composite face effects, as well as (3) comparable global precedence effect in the Navon task. Interestingly, the same pattern of preserved and impaired holistic processing was observed in a second evaluation of DS four years later. While these findings suggest that holistic processing deficits in Acquired Prosopagnosia may be task-specific and persist over time—pointing toward the potential chronicity of the impairment—they should be interpreted with caution, given the floor effects and the single-case design.

Source: Manual

Persistent task-specific impairment of holistic face processing in acquired prosopagnosia.

Authors: Leong, B.Q.Z., Hussain Ismail, A.M. and Estudillo, A.J.

Journal: Scientific reports

Volume: 15

Issue: 1

Pages: 43115

eISSN: 2045-2322

ISSN: 2045-2322

DOI: 10.1038/s41598-025-28666-3

Abstract:

Face recognition deficits observed in Acquired Prosopagnosia are typically associated with impaired holistic processing. Nonetheless, whether this deficit is task-dependent, face-specific, and persistent over time has been under investigated. The present study examined the role of holistic processing in a case of acquired prosopagnosia (Patient DS). Patient DS, along with several neurotypical participants, completed the three standard measures of holistic face processing: the face inversion, part-whole, and composite face tasks, as well as a measure of non-face global processing: the Navon task. Our single-case analyses indicated that, compared to neurotypical participants, DS showed (1) impaired inversion effects, but (2) comparable part-whole and composite face effects, as well as (3) comparable global precedence effect in the Navon task. Interestingly, the same pattern of preserved and impaired holistic processing was observed in a second evaluation of DS four years later. While these findings suggest that holistic processing deficits in Acquired Prosopagnosia may be task-specific and persist over time-pointing toward the potential chronicity of the impairment-they should be interpreted with caution, given the floor effects and the single-case design.

Source: Europe PubMed Central