Dr Emilie Hardouin
- 01202 962402
- ehardouin at bournemouth dot ac dot uk
- http://orcid.org/0000-0002-2031-5160
- Associate Professor and Deputy Head of Department
- Christchurch House C106, Talbot Campus, Fern Barrow, Poole, BH12 5BB
- Keywords:
- Biodiversity
- Biology
- Ecology
- Population
Biography
Dr. Emilie Hardouin joined Bournemouth University in May 2012 and is now an associate lecturer in conservation genetics. Her research focuses on the distribution and mechanisms of rapid adaptation of invasive species. She completed her PhD at the Max-Planck-Institute for Evolutionary Biology (MPI), Germany (2007-2011) after an MSc in Genetic from the University Paris 7, France.
During her PhD and Post-Doctoral fellowship (02/2011 - 05/2012) at the MPI, she was under the supervision of Prof. Dietahrd Tautz one of the world leaders in the field of evolutionary genetics and closely worked with internationally well-known evolutionary biologists. Her interest was in the mechanisms and the identification of genes involved in adaptive processes using different techniques such as microsatellite genome-wide screening (Hardouin 2011 PhD thesis) and complete
mitochondrial genome sequencing (Hardouin et al. 2013). She studied the colonization history and dynamic of the house mouse from the Kerguelen Archipelago (Hardouin et al... 2010). Over the years, Dr. Hardouin used several molecular methods such as mitochondria sequencing (Hardouin et al.
2010, Hardouin et al. 2013, Gabriel et al in prep), microsatellites genotyping (Hardouin et al. 2010, Linnenbrink et al. 2013, Hardouin et al. in prep), RFLP (Myles et al. 2011), cellular assay (Byrk et al. 2008) or even morphometrics (Renaud et al. 2013). She already has 6 publications in high impact factor journal such as Biology Letter or Molecular Ecology. Her research has been well received in all the 3 international workshops and 11 national and international conferences that she attended. Furthermore, she developed an international network of collaborators in top universities such as Cornell (USA), Lyon (France), Adelaide (Australia), Stellenbosch (South Africa), Montpellier (France), Max Planck Institute for Evolutionary Biology (Germany) and Kiel (Germany).
(Germany). She is also a referee for Molecular Ecology and the Protist.
moreResearch
My research focuses on the distribution and mechanisms of rapid adaptation of invasive species. The aim is to understand the invasive potential of species using phylogeography, to identify how genetic processes and plasticity drive invasion patterns and to understand rapid adaptation to a new habitat.
1- Population genetics of a global invasion:
The research aim is to use the invasive fish topmouth gudgeon Pseudorasbora parva (TMG) as a model species to identify how genetic processes and plasticity drive invasion patterns at global scales. Native to China and introduced to Europe in the 1960s, TMG have invaded more than 30 countries, causing concern over competitive interactions and novel disease introduction. By adding fine-scale genetic data to previous work on species' ecology and morphology, the research will derive a much finer understanding of their invasion process. This project has two different components: (1) investigate TMG phylogeography across their native (Asia) and invasive (Europe) ranges through their genetic diversity, structure and distribution; and (2) quantify the roles of plasticity and selection in the TMG invasion process through combining genetic, biogeographic and morphological approaches to enable the building of predictive models of invasion.
2- On the tracks of the Phoenician’s through genomic phylogeographic studies of Mediterranean mice.
Coming from the Near East, the western house mouse first spread to the Mediterranean and then around much of the world using human mediated transport... It is known that the westward mouse diffusion started 3000 years ago (Iron Age). Interestingly, at this time, the Phoenicians were establishing commercial routes up to Gibraltar, making Phoenician movements the likely explanation for the mouse colonisation of the Mediterranean. I am using the state-of-the-art genomic phylogeography, geometric morphometrics and statistical analysis to infer population history, evolution and dispersal of mice.
moreFavourites
- Hardouin, E.A., Butler, H., Cvitanović, M., Ulrich, R.G., Schulze, V., Schilling, A.K., Lurz, P.W.W., Meredith, A. and Hodder, K.H., 2021. Wildlife conservation in a fragmented landscape: the Eurasian red squirrel on the Isle of Wight. Conservation Genetics, 22 (4), 571-583.
- Hardouin, E.A., Liang, W.J., Hodder, K.H. et al., 2019. Conservation of genetic uniqueness in remaining populations of red squirrels (Sciurus vulgaris L.) in the South of England. Ecology and Evolution, 9 (11), 6547-6558.
- Pedreschi, D., Cantarello, E., Diaz, A., Golicher, D., Korstjens, A.H., Gillingham, P., Hardouin, E.A., Stewart, J.R. et al., 2019. Challenging the European southern refugium hypothesis: Species-specific structures versus general patterns of genetic diversity and differentiation among small mammals. Global Ecology and Biogeography, 28 (2), 262-274.
- García-Rodríguez, O. et al., 2018. Cyprus as an ancient hub for house mice and humans. Journal of Biogeography, 45 (12), 2619-2630.
- Renaud, S., Ledevin, R., Pisanu, B., Chapuis, J.-L., Quillfeldt, P. and Hardouin, E.A., 2018. Divergent in shape and convergent in function: Adaptive evolution of the mandible in Sub-Antarctic mice. EVOLUTION, 72 (4), 878-892.
Journal Articles
- Renaud, S., Ledevin, R., Dufour, A.B., Romestaing, C. and Hardouin, E.A., 2024. Molar wear in house mice: Insight into diet preferences at an ecological timescale? Biological Journal of the Linnean Society, 141 (2), 289-305.
- Hardouin, E.A., Andreou, D. et al., 2024. Population genetics and demography of the endemic mouse species of Cyprus, Mus cypriacus. Mammalian Biology.
- Renaud, S., Ledevin, R., Romestaing, C. and Hardouin, E., 2023. 3D models related to the publication: “Molar wear in house mice: insight into diet preferences at an ecological time scale?”. MorphoMuseuM, 9 (3).
- Boakes, Z., Stafford, R., Bramer, I., Cvitanović, M. and Hardouin, E.A., 2023. The importance of urban areas in supporting vulnerable and endangered mammals. Urban Ecosystems.
- Sun, C.H., Hardouin, E.A. et al., 2022. The role of ancestral seascape discontinuity and geographical distance in structuring rockfish populations in the Pacific Northwest. Frontiers in Marine Science, 9.
- Antognazza, C.M., Sabatino, S.J., Britton, R.J., Hillman, R.J., Aprahamian, M., Hardouin, E.A. and Andreou, D., 2022. Hybridization and genetic population structure of Alosa population in the United Kingdom. Journal of Fish Biology, 101 (2), 408-413.
- Antognazza, C.M., Britton, J.R., De Santis, V., Kolia, K., Turunen, O.A., Davies, P., Allen, L., Hardouin, E.A., Crundwell, C. and Andreou, D., 2021. Environmental DNA reveals the temporal and spatial extent of spawning migrations of European shad in a highly fragmented river basin. Aquatic Conservation: Marine and Freshwater Ecosystems, 31 (8), 2029-2040.
- Hardouin, E.A., Butler, H., Cvitanović, M., Ulrich, R.G., Schulze, V., Schilling, A.K., Lurz, P.W.W., Meredith, A. and Hodder, K.H., 2021. Wildlife conservation in a fragmented landscape: the Eurasian red squirrel on the Isle of Wight. Conservation Genetics, 22 (4), 571-583.
- Antognazza, C.M. et al., 2021. Application of eDNA metabarcoding in a fragmented lowland river: Spatial and methodological comparison of fish species composition. Environmental DNA, 3 (2), 458-471.
- García-Rodríguez, O., Hardouin, E.A., Hambleton, E., Monteith, J., Randall, C., Richards, M.B., Edwards, C.J. and Stewart, J.R., 2021. Ancient mitochondrial DNA connects house mice in the British Isles to trade across Europe over three millennia. BMC ecology and evolution, 21 (1), 9.
- Andreou, D., Hardouin, E.A., Stewart, J.R., Britton, J.R. et al., 2020. Vicariance in a generalist fish parasite driven by climate and salinity tolerance of hosts. Parasitology, 147 (14), 1658-1664.
- Renaud, S. et al., 2020. Morphometrics and genetics highlight the complex history of Eastern Mediterranean spiny mice. Biological Journal of the Linnean Society, 130 (3), 599-614.
- Sana, S., Hardouin, E.A., Paley, R., Zhang, T. and Andreou, D., 2020. The complete mitochondrial genome of a parasite at the animal-fungal boundary. Parasites and Vectors, 13 (1).
- Hardouin, E.A., Liang, W.J., Hodder, K.H. et al., 2019. Conservation of genetic uniqueness in remaining populations of red squirrels (Sciurus vulgaris L.) in the South of England. Ecology and Evolution, 9 (11), 6547-6558.
- Renaud, S., Delepine, C., Ledevin, R., Pisanu, B., Quere, J.-P. and Hardouin, E., 2019. A sharp incisor tool for predator house mice back to the wild. Journal of Zoological Systematics and Evolutionary Research.
- Pedreschi, D., Cantarello, E., Diaz, A., Golicher, D., Korstjens, A.H., Gillingham, P., Hardouin, E.A., Stewart, J.R. et al., 2019. Challenging the European southern refugium hypothesis: Species-specific structures versus general patterns of genetic diversity and differentiation among small mammals. Global Ecology and Biogeography, 28 (2), 262-274.
- Antognazza, C.M., Britton, J.R., Potter, C., Franklin, E., Hardouin, E.A., Gutmann Roberts, C., Aprahamian, M. and Andreou, D., 2019. Environmental DNA as a non-invasive sampling tool to detect the spawning distribution of European anadromous shads (Alosa spp.). Aquatic Conservation: Marine and Freshwater Ecosystems, 29 (1), 148-152.
- García-Rodríguez, O. et al., 2018. Cyprus as an ancient hub for house mice and humans. Journal of Biogeography, 45 (12), 2619-2630.
- Hardouin, E.A., Andreou, D., Zhao, Y., Chevret, P., Fletcher, D.H., Britton, J.R. and Gozlan, R.E., 2018. Reconciling the biogeography of an invader through recent and historic genetic patterns: the case of topmouth gudgeon Pseudorasbora parva. Biological Invasions, 20 (8), 2157-2171.
- Sana, S., Williams, C., Hardouin, E.A., Blake, A., Davison, P., Pegg, J., Paley, R., Zhang, T. and Andreou, D., 2018. Phylogenetic and environmental DNA insights into emerging aquatic parasites: implications for risk management. International Journal for Parasitology, 48 (6), 473-481.
- Renaud, S., Ledevin, R., Pisanu, B., Chapuis, J.-L., Quillfeldt, P. and Hardouin, E.A., 2018. Divergent in shape and convergent in function: Adaptive evolution of the mandible in Sub-Antarctic mice. EVOLUTION, 72 (4), 878-892.
- Sana, S., Hardouin, E.A., Gozlan, R.E., Ercan, D., Tarkan, A.S., Zhang, T. and Andreou, D., 2017. Origin and invasion of the emerging infectious pathogen Sphaerothecum destruens. Emerging microbes & infections, 6 (8), e76.
- Sana, Hardouin, Gozlan, Tarkan, Ercan, Zhang and Andreou, 2017. Origin and invasion of emerging infectious pathogen sphaerothecum destruens. Emerging Microbes and Infections.
- Renaud, S., Hardouin, E.A., Quere, J.P. and Chevret, P., 2017. Morphometric variations at an ecological scale: Seasonal and local variations in feral and commensal house mice. Mammalian Biology - Zeitschrift für Säugetierkunde.
- Ledevin, R., Hardouin, E.A. et al., 2016. Phylogeny and adaptation shape the teeth of insular mice. Proceedings of the Royal Society B.
- Renaud, S., Dufour, A.-B., Hardouin, E., Ledevin, R. and Auffray, J.-C., 2015. Once upon Multivariate Analyses: When They Tell Several Stories about Biological Evolution. PLoS One.
- Hardouin, E.A., Orth, A., Teschke, M., Darvish, J., Tautz, D. and Bonhomme, F., 2015. Eurasian house mouse (Mus musculus L.) differentiation at microsatellite loci identifies the Iranian plateau as a phylogeographic hotspot. BMC Evolutionary Biology.
- Renaud, S., Gomes Rodrigues, H., Ledevin, R., Pisanu, B., Chapuis, J.-L. and Hardouin, E.A., 2015. Fast evolutionary response of house mice to anthropogenic disturbance on a Sub-Antarctic island. Biological Journal of the Linnean Society, 114, 513-526.
- Renaud, S., Hardouin, E.A., Pisanu, B. and Chapuis, J.-L., 2013. Invasive house mice facing a changing environment on the Sub-Antarctic Guillou Island (Kerguelen Archipelago). J Evol Biol, 26 (3), 612-624.
- Renaud, S., Hardouin, E.A., Pisanu, B. and Chapuis, J.L., 2013. Invasive house mice facing a changing environment on the Sub-Antarctic Guillou Island (Kerguelen Archipelago). Journal of Evolutionary Biology, 26 (3), 612-624.
- Linnenbrink M, Wang J, Hardouin EA, Künzel S, Metzler D and Baines JF, 2013. The role of biogeography in shaping diversity of the intestinal microbia in house mouse. Molecular Ecology.
- Hardouin EA and Tautz D, 2013. Increased mitochondrial mutation frequency after an island colonization: positive selection or accumulation of slightly deleterious mutations? Biology Letters, 9.
- Hardouin EA and Tautz D, 2013. Increased mitochondrial mutation frequency after an island colonization: positive selection or accumulation of slightly deleterious mutations? Biology Letters, 9 (2).
- Myles, S., Hardouin, E. et al., 2011. Testing the thrifty gene hypothesis: the Gly482Ser variant in PPARGC1A is associated with BMI in Tongans. BMC Med Genet, 12, 10.
- Hardouin, E.A., Chapuis, J.-L., Stevens, M.I., Van Vuuren, J.B., Quillfeldt, P., Scavetta, R.J., Teschke, M. and Tautz, D., 2010. House mouse colonization patterns on the sub-Antarctic Kerguelen Archipelago suggest singular primary invasions and resilience against re-invasion. BMC Evolutionary Biology, 10 (325).
- Bryk, J., Hardouin, E., Pugach, I., Hughes, D., Strotmann, R., Stoneking, M. and Myles, S., 2008. Positive selection in East Asians for an EDAR allele that enhances NF-kappaB activation. PLoS One, 3 (5), e2209.
Conferences
- Renaud, S., Ledevin, R., Delepine, C., Pisanu, B., Quillfedt, P. and Hardouin, E.A., 2019. Diet Shift in Sub-Antarctic Mice: Morpho-Functional Response of the Jaw System. JOURNAL OF MORPHOLOGY, 280, S68.
- Hardouin E.A., 2014. Mice invasion of the sub-Antarctic Kerguelen Archipelago. In: 14th Rodens et Spatium, 28 July-2 September 2014 Lisbon, Portugal.
- Hardouin E.A. and Bonhomme F., 2014. What have we learned from microsatellites, what could be learned from NGS in the highly structured M. musculus species complex? In: Tautz, ed. Workshop on wild mice 22-25 May 2014 Ploen, Germany.
Reports
- Pinder, A., Andreou, D., Hardouin, E., Sana, S., Gillingham, P. and Gutmann-Roberts, C., 2016. Spawning Success and Population Structure of Shad (Alosa spp.) in the River Teme, 2015: with supplementary note on Sea Lamprey spawning. BUG.
PhD Students
- Nigel Haywood, 2018. Genetic and environmental factors in the conservation of the Falkland fritillary, Yramea cytheris cytheris
- Oxala Garcia Rodriguez, 2018. Human Biogeography: Comparative Phylogeography of Modern Humans and other Organisms
- Adrian Blake. Genetic pedigrees and individual trait variability: ecological and evolutionary consequences for wild fish populations
Profile of Teaching PG
- Conservation Genetics
Profile of Teaching UG
- Evolution and Conservation Wildlife
Grants
- ECO-CODING: Creating a centre for DNA Meta-barcoding Ecology at BU (HEIF (Higher Education Innovation Fund), 31 Jul 2016). Awarded
- Deciphering cryptic biodiversity and Eve’s origin. (Fusion Fund, Bournemouth University, 01 Apr 2014). Awarded
- Networking and sampling trip: Inferring human influence using house mouse as a proxy on Cyprus. (Fusion Fund, Bournemouth University, 01 Aug 2013). Awarded
- Monitoring Allis and Twait Shad (Natural Resources Wales, 15 May 2013). In Progress
- Ecology and systematics of new microbial consortia in oxygen-depleted aquatic habitats (Fusion Fund, Bournemouth University, 15 Apr 2013). Awarded
- Multi-disciplinary approaches to understand biological invasions (FSBI, 01 Mar 2013). Awarded
Qualifications
- PhD in Evolutionary Biology (Christian-Albrechts-Universität zu Kiel, Germany, 2011)
Memberships
- BES, Member,